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Substance Name: Isonipecotic acid, 1-methyl-4-phenyl-, ethyl ester, 1-oxide, hydrochloride
RN: 4956-15-4
InChIKey: HWLYBYWUQNGVTB-UHFFFAOYSA-M

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C15-H21-N-O3.Cl-H

Molecular Weight

  • 298.788
 
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Names and Synonyms

Synonyms

  • 1-Methyl-4-phenylisonipecotic acid ethyl ester 1-oxide hydrochloride
  • Dolantin N-oxide hydrochloride

Systematic Name

  • Isonipecotic acid, 1-methyl-4-phenyl-, ethyl ester, 1-oxide, hydrochloride

Registry Numbers

CAS Registry Number

  • 4956-15-4

System Generated Number

  • 0004956154

Molecular Formulas

Molecular Formula

  • C15-H21-N-O3.Cl-H

Molecular Formula Fragments

  • C15-H21-N-O3
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C15H21NO3.ClH/c1-3-19-14(17)15(13-7-5-4-6-8-13)9-11-16(2,18)12-10-15;/h4-8H,3,9-12H2,1-2H3;1H/p-1

InChIKey

HWLYBYWUQNGVTB-UHFFFAOYSA-M

Smiles

C1(c2ccccc2)(CC[N+](C)([O-])CC1)C(OCC)=O.[ClH-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mammal (species unspecified) LD50 unreported 200mg/kg (200mg/kg)   Archivum Immunologiae et Therapiae Experimentalis. Vol. 14, Pg. 121, 1966.
mouse LD50 intraperitoneal 575mg/kg (575mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Archivum Immunologiae et Therapiae Experimentalis. Vol. 15, Pg. 290, 1967.
mouse LD50 intravenous 300mg/kg (300mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Archivum Immunologiae et Therapiae Experimentalis. Vol. 15, Pg. 290, 1967.
mouse LD50 oral 2gm/kg (2000mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Archivum Immunologiae et Therapiae Experimentalis. Vol. 15, Pg. 290, 1967.
mouse LD50 subcutaneous 975mg/kg (975mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Archivum Immunologiae et Therapiae Experimentalis. Vol. 15, Pg. 290, 1967.