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Substance Name: Trientine tetrahydrochloride
RN: 4961-40-4
UNII: 7360URE56Q
InChIKey: OKHMDSCYUWAQPT-UHFFFAOYSA-N

Note

  • Used as stabilizer for epoxy resins, as ampholyte for isoelectric focusing and as chelating agent for copper in hepatolenticular degeneration; may cause liver damage.

Molecular Formula

  • C6-H18-N4.4Cl-H

Molecular Weight

  • 292.08
 
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Names and Synonyms

Results Name

  • Trientine tetrahydrochloride

Name of Substance

  • Trientine tetrahydrochloride

Synonyms

  • EINECS 225-604-3
  • N,N'-Bis(2-aminoethyl)-1,2-ethanediamine tetrahydrochloride
  • NSC 158271
  • Trientine HCl
  • Trientine tetrahydrochloride
  • Triethylenetetramine, tetrahydrochloride
  • UNII-7360URE56Q

Systematic Names

  • 1,2-Ethanediamine, N,N'-bis(2-aminoethyl)-, tetrahydrochloride
  • 1,2-Ethanediamine, N1,N2-bis(2-aminoethyl)-, hydrochloride (1:4)
  • 3,6-Diazaoctane-1,8-diamine tetrahydrochloride

Registry Numbers

CAS Registry Number

  • 4961-40-4

FDA UNII

  • 7360URE56Q

Other Registry Number

  • 181589-66-2

System Generated Number

  • 0004961404

Molecular Formulas

Molecular Formula

  • C6-H18-N4.4Cl-H

Molecular Formula Fragments

  • C6-H18-N4
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C6H18N4.4ClH/c7-1-3-9-5-6-10-4-2-8;;;;/h9-10H,1-8H2;4*1H

InChIKey

OKHMDSCYUWAQPT-UHFFFAOYSA-N

Smiles

NCCNCCNCCN.Cl.Cl.Cl.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 intraperitoneal 657mg/kg (657mg/kg)   Research Communications in Chemical Pathology and Pharmacology. Vol. 14, Pg. 153, 1976.
rat LD50 oral 2285mg/kg (2285mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Toxicology Letters. Vol. (Suppl), Pg. 246, 1992.