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Substance Name: Eltrombopag olamine [USAN:JAN]
RN: 496775-62-3
UNII: 4U07F515LG
InChIKey: PLILLUUXAVKBPY-SBIAVEDLSA-N

Note

  • An oral, nonpeptide thrombopoietin receptor agonist.

Classification Code

  • Treatment of Chemotherapy-Induced Thrombocytopenia and Treatment of Immune Thrombocytopenic Purpura

Molecular Formula

  • C25-H22-N4-O4.2(C2-H7-N-O)

Molecular Weight

  • 564.6394
 

Names and Synonyms

Name of Substance

  • Eltrombopag olamine
  • Eltrombopag olamine [USAN:JAN]

Synonyms

  • 3'-((2Z)-2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)diazanyl)-2'-hydroxybiphenyl-3-carboxylic acid compound with 2-aminoethanol (1:2)
  • Eltrombopag olamine
  • Promacta
  • Revolade
  • SB 497115GR
  • SB-497115-GR
  • UNII-4U07F515LG

Systematic Name

  • (1,1'-Biphenyl)-3-carboxylic acid, 3'-((2Z)-(1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene)hydrazino)-2'-hydroxy, compound with 2-Aminoethanol (1:2)

Registry Numbers

CAS Registry Number

  • 496775-62-3

FDA UNII

  • 4U07F515LG

System Generated Number

  • 0496775623

Molecular Formulas

Molecular Formula

  • C25-H22-N4-O4.2(C2-H7-N-O)

Molecular Formula Fragments

  • C2-H7-N-O
  • C25-H22-N4-O4
  • COMPONENT

Structure Descriptors

InChI

1S/C25H22N4O4.2C2H7NO/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33;2*3-1-2-4/h4-13,26,30H,1-3H3,(H,32,33);2*4H,1-3H2/b27-22-;;

InChIKey

PLILLUUXAVKBPY-SBIAVEDLSA-N

Smiles

Cc1ccc(cc1C)N2C(=O)/C(=N\Nc3cccc(c3O)c4cccc(c4)C(=O)O)/C(=N2)C.C(CO)N.C(CO)N