Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Antibiotic G 418
RN: 49863-47-0
UNII: A08F5XTI6G
InChIKey: BRZYSWJRSDMWLG-DJWUNRQOSA-N

Note

  • From Micromonospora rhodorangea.

Molecular Formula

  • C20-H40-N4-O10

Molecular Weight

  • 496.554
 

Classification Codes

  • Amebicides
  • Anti-Infective Agents
  • Antiparasitic Agents
  • Antiprotozoal Agents
  • Coccidiostats
  • Drug / Therapeutic Agent
  • Mutation Data
  • Natural Product
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Antibiotic G 418

Synonyms

  • Antibiotic G418
  • BRN 1669188
  • G 418
  • Geneticin
  • UNII-A08F5XTI6G

Systematic Names

  • D-Streptamine, O-2-amino-2,7-dideoxy-D-glycero-alpha-D-gluco-heptopyranosyl-(1-4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6))-
  • O-2-Amino-2,7-dideoxy-D-glycero-alpha-D-gluco-heptopyranosyl-(1-4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6))-D-streptamine

Registry Numbers

CAS Registry Number

  • 49863-47-0

FDA UNII

  • A08F5XTI6G

Other Registry Numbers

  • 49662-03-5
  • 83855-92-9

System Generated Number

  • 0049863470

Structure Descriptors

InChI

1S/C20H40N4O10/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19/h6-19,24-30H,4-5,21-23H2,1-3H3/t6-,7+,8-,9-,10-,11+,12+,13-,14-,15-,16+,17-,18-,19-,20+/m1/s1

InChIKey

BRZYSWJRSDMWLG-DJWUNRQOSA-N

Smiles

O1[C@@H]([C@@H]([C@@H](O)[C@@H]([C@H]1[C@H](O)C)O)N)O[C@H]1[C@@H]([C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@](CO2)(O)C)O)[C@H](N)C[C@@H]1N)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 140mg/kg (140mg/kg)   "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 1, Pg. 177, 1980.