Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Tioxolone [INN:BAN:DCF]
RN: 4991-65-5
UNII: S0FAJ1R9CD
InChIKey: SLYPOVJCSQHITR-UHFFFAOYSA-N

Note

  • Antiseborrheic agent.

Molecular Formula

  • C7-H4-O3-S

Molecular Weight

  • 168.172
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • 1,3-Benzoxathiol-2-one, 6-hydroxy-
  • 6-Hydro-2-oxo-1,3-benzoxathiole
  • 6-Hydroxy-1,3-benzoxathiol-2-one
  • Thioxolone
  • Tioxolone
  • Tioxolone [INN:BAN:DCF]

Synonyms

  • EINECS 225-653-0
  • Thioxolone
  • Tioxolona
  • Tioxolona [INN-Spanish]
  • Tioxolone
  • Tioxolonum
  • Tioxolonum [INN-Latin]
  • UNII-S0FAJ1R9CD

Systematic Names

  • 6-Hydroxy-1,3-benzoxathiol-2-one
  • Tioxolone

Registry Numbers

CAS Registry Number

  • 4991-65-5

FDA UNII

  • S0FAJ1R9CD

System Generated Number

  • 0004991655

Structure Descriptors

InChI

1S/C7H4O3S/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3,8H

InChIKey

SLYPOVJCSQHITR-UHFFFAOYSA-N

Smiles

c1(ccc2sc(oc2c1)=O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LC50 inhalation 3710mg/m3 (3710mg/m3) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 64(3), Pg. 63, 1999.
rat LD50 oral 633mg/kg (633mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

BLOOD: HEMORRHAGE
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 64(3), Pg. 63, 1999.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 160 deg C   EXP
log P (octanol-water) 1.670 (none)   EST
Atmospheric OH Rate Constant 1.97E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.