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Substance Name: Ergocalciferol [USP:INN:BAN:JAN]
RN: 50-14-6
UNII: VS041H42XC
InChIKey: MECHNRXZTMCUDQ-RKHKHRCZSA-N
Note
- Derivatives of ERGOSTEROL formed by ULTRAVIOLET RAYS breaking of the C9-C10 bond. They differ from CHOLECALCIFEROL in having a double bond between C22 and C23 and a methyl group at C24.
Molecular Formula
- C28-H44-O
Molecular Weight
- 396.6546
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Agricultural Chemical
- Antiviral (COVID-19)
- Bone Density Conservation Agents
- Calcium-Regulating Hormones and Agents
- Drug / Therapeutic Agent
- Growth Substances
- Human Data
- Micronutrients
- Reproductive Effect
- Rodenticide
- Vitamin (Antirachitic)
- Vitamins
Superlist Classification Code
- Threshold Planning Quantity (TPQ) = 1000/10000 lb
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NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
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Names and Synonyms
Name of Substance
- Ergocalciferol
- Ergocalciferol [USP:INN:BAN:JAN]
- Viosterol
- Vitamin D2
MeSH Heading
- Ergocalciferols
Synonyms
- (+)-Vitamin D2
- (3-beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10,(19),22-tetraen-3-ol
- 9,10-Seco(5Z,7E,22E)-5,7,10(19),22-ergostatetraen-3-ol
- 9,10-Secoergosta-5,7,10(19),22-tetraen-3-beta-ol
- Activated ergosterol
- Buco-D
- Calciferol
- Calciferolum
- Calciferon 2
- Condocaps
- Condol
- Crystallina
- D-Arthin
- D-Tracetten
- Daral
- Davitamon D
- Davitin
- De-rat concentrate
- Decaps
- Dee-Osterol
- Dee-Ron
- Dee-Ronal
- Dee-Roual
- Deltalin
- Deratol
- Detalup
- Diactol
- Disdrol
- Divit urto
- Doral [Vitamin Derivative]
- Drisdol
- EINECS 200-014-9
- Ergocalciferol
- Ergocalciferolo
- Ergocalciferolo [DCIT]
- Ergocalciferolum
- Ergocalciferolum [INN-Latin]
- Ergorone
- Ertron
- Fortodyl
- Geltabs
- HI-Deratol
- HSDB 819
- Hyperkil
- Infron
- Irradiated ergosta-5,7,22-trien-3-beta-ol
- Metadee
- Mina D2
- Mulsiferol
- Mykostin
- Novovitamin-D
- NSC 62792
- Oleovitamin D2
- Ostelin
- Radiostol
- Radsterin
- Rodine C
- Rodinec
- Shock-ferol
- Sorex C.R.
- Sterogyl
- UNII-VS041H42XC
- Vigantol
- Vio-D
- Viosterol
- Vitamin D2
- Vitavel-D
Systematic Names
- 9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol, (3beta,5Z,7E,22E)-
- Cyclohexanol, 4-methylene-3-((2E)-2-((1R,3aS,7aR)-octahydro-7a-methyl-1-((1R,2E,4R)-1,4,5-trimethyl-2-hexen-1-yl)-4H-inden-4-ylidene)ethylidene)-, (1S,3Z)-
- Ergocalciferol
Superlist Names
- 9,10-Seco(5Z,7E,22E)-5,7,10(19),22-ergostatetraen-3-ol
- Ergocalciferol
- Vitamin D2
Mixture Names
- Geltabs Vitamin D
- Haliver
Registry Numbers
CAS Registry Number
- 50-14-6
FDA UNII
- VS041H42XC
Other Registry Numbers
- 1384584-60-4
- 31316-19-5
- 7489-18-1
- 8017-28-5
System Generated Number
- 0000050146
Structure Descriptors
InChI
InChI=1S/C28H44O/c1-19(2)20(3)9-10-22(5)26-15-16-27-23(8-7-17-28(26,27)6)12-13-24-18-25(29)14-11-21(24)4/h9-10,12-13,19-20,22,25-27,29H,4,7-8,11,14-18H2,1-3,5-6H3/b10-9+,23-12+,24-13-/t20-,22+,25-,26+,27-,28+/m0/s1InChIKey
MECHNRXZTMCUDQ-RKHKHRCZSA-NSmiles
CC(C)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LDLo | oral | 5mg/kg (5mg/kg) | Drugs in Japan Vol. 6, Pg. 128, 1982. | |
dog | LDLo | intramuscular | 5mg/kg (5mg/kg) | Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 116, Pg. 138, 1950. | |
dog | LDLo | intraperitoneal | 10mg/kg (10mg/kg) | GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: FLUID INTAKE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 116, Pg. 138, 1950. |
dog | LDLo | intravenous | 5mg/kg (5mg/kg) | Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 116, Pg. 138, 1950. | |
dog | LDLo | oral | 4mg/kg (4mg/kg) | GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 116, Pg. 138, 1950. |
duck | LD50 | oral | > 2gm/kg (2000mg/kg) | Defense des Vegetaux. Vol. 43(255-256), Pg. 14, 1989. | |
guinea pig | LDLo | oral | 40mg/kg (40mg/kg) | Drugs in Japan Vol. 6, Pg. 128, 1982. | |
mouse | LD50 | oral | 23700ug/kg (23.7mg/kg) | Pesticide Manual. Vol. 9, Pg. 115, 1991. | |
rat | LD50 | oral | 10mg/kg (10mg/kg) | "Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson Publications, 1976/77 revisionVol. 3, Pg. 132, 1986. | |
women | TDLo | oral | 12600ug/kg/72 (12.6mg/kg) | GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: ANOREXIA (HUMAN | Lancet. Vol. 1, Pg. 1164, 1980. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 116.5 | deg C | EXP | |
log P (octanol-water) | 10.44 | (none) | EST | |
Water Solubility | 50 | mg/L | EXP | |
Atmospheric OH Rate Constant | 3.53E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.