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Substance Name: Corticosterone
RN: 50-22-6
UNII: W980KJ009P
InChIKey: OMFXVFTZEKFJBZ-HJTSIMOOSA-N

Note

  • An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)

Molecular Formula

  • C21-H30-O4

Molecular Weight

  • 346.464
 

Classification Codes

  • Anti-Inflammatory Agents
  • Drug / Therapeutic Agent
  • Mutation Data
  • Reproductive Effect

Names and Synonyms

Name of Substance

  • Corticosterone

MeSH Heading

  • Corticosterone

Synonyms

  • (11-beta)-11,21-Dihydroxypregn-4-ene-3,20-dione
  • 11,12-Dihydroxyprogesterone
  • 11-beta,21-Dihydroxypregn-3,20-dione
  • 11-beta,21-Dihydroxyprogesterone
  • 11-Hydroxycorticoaldosterone
  • 11beta,21-Dihydroxyprogesterone
  • 17-Deoxycortisol
  • 4-08-00-02907 (Beilstein Handbook Reference)
  • 4-Pregnene-11-beta,21-diol-3,20-dione
  • 4-Pregnene-11beta,21-diol-3,20-dione
  • BRN 2339601
  • CCRIS 6753
  • Compound B
  • Compound B nach Kendall
  • Corticosteron
  • Corticosterone
  • EINECS 200-019-6
  • Kendall's compound B
  • NSC 9705
  • Pregn-4-ene-3,20-dione, 11-beta,21-dihydroxy-
  • Pregn-4-ene-3,20-dione, 11beta,21-dihydroxy-
  • Reichstein's B
  • Reichstein's substance H
  • Substanz H nach Reichstein
  • UNII-W980KJ009P

Systematic Names

  • Corticosterone
  • Pregn-4-ene-3,20-dione, 11,21-dihydroxy-, (11beta)-

Registry Numbers

CAS Registry Number

  • 50-22-6

FDA UNII

  • W980KJ009P

System Generated Number

  • 0000050226

Structure Descriptors

InChI

1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1

InChIKey

OMFXVFTZEKFJBZ-HJTSIMOOSA-N

Smiles

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C)O

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 181 deg C   EXP
log P (octanol-water) 1.94 (none)   EXP
Water Solubility 199 mg/L 25 EXP
Vapor Pressure 4.74E-12 mm Hg 25 EST
Henry's Law Constant 3.70E-10 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.16E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.