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Substance Name: DDT [BSI:ISO]
RN: 50-29-3
UNII: CIW5S16655
InChIKey: YVGGHNCTFXOJCH-UHFFFAOYSA-N
Note
- A polychlorinated pesticide that is resistant to destruction by light and oxidation. Its unusual stability has resulted in difficulties in residue removal from water, soil, and foodstuffs. This substance may reasonably be anticipated to be a carcinogen: Fourth Annual Report on Carcinogens (NTP-85-002, 1985). (From Merck Index, 11th ed).
Molecular Formula
- C14-H9-Cl5
Molecular Weight
- 354.4901
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Agricultural Chemical
- Human Data
- Insecticide
- Mutation Data
- Reproductive Effect
- TSCA Flag S (Substance is Identified in a Final Significant New Use Rule)
- Tumor Data
Superlist Classification Codes
- 2007 CERCLA Priority List, Rank: 12
- 2011 CERCLA Priority List, Rank: 13
- Overall Carcinogenic Evaluation: Group 2B
- Reasonably Anticipated to be a Carcinogen
- Reportable Quantity (RQ) = 1 lb
- TWA 1 mg/m3; Confirmed animal carcinogen with unknown relevance to humans
- TWA 1 mg/m3; skin
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Names and Synonyms
Results Name
- DDT [BSI:ISO]
Name of Substance
- Chlorophenothane [NF]
- Clofenotane [INN]
- DDT
- DDT [BSI:ISO]
MeSH Heading
- DDT
Synonyms
- 1,1'-(2,2,2-Trichloroethylidene)bis(4-chlorobenzene)
- 1,1,1-Trichloor-2,2-bis(4-chloor fenyl)-ethaan
- 1,1,1-Trichloor-2,2-bis(4-chloor fenyl)-ethaan [Dutch]
- 1,1,1-Trichlor-2,2-bis(4-chlor-phenyl)-aethan
- 1,1,1-Trichlor-2,2-bis(4-chlor-phenyl)-aethan [German]
- 1,1,1-Trichloro-2,2-bis(4,4'-dichlorodiphenyl)ethane
- 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane
- 1,1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane
- 1,1,1-Trichloro-2,2-di(4-chlorophenyl)-ethane
- 1,1,1-Tricloro-2,2-bis(4-cloro-fenil)-etano
- 1,1,1-Tricloro-2,2-bis(4-cloro-fenil)-etano [Italian]
- 1,1,1-Tricloro-2,2-bis(4-cloro-fenyl)-etano
- 1,1,1-Tricloro-2,2-bis(4-cloro-fenyl)-etano [Italian]
- 1,1-Bis-(p-chlorophenyl)-2,2,2-trichloroethane
- 2,2-Bis(p-chlorophenyl)-1,1,1-trichloroethane
- 4,4'-DDT
- 4,4'-Dichlorodiphenyltrichloroethane
- 4-05-00-01885 (Beilstein Handbook Reference)
- Aavero-extra
- Agritan
- AI3-01506
- alpha,alpha-Bis(p-chlorophenyl)-beta,beta,beta-trichloroethane
- Anofex
- Arkotine
- Azotox M 33
- Benzochloryl
- Bosan Supra
- Bovidermol
- BRN 1882657
- Caswell No. 308
- CCRIS 194
- Chlofenotan
- Chlorophenothan
- Chlorophenothane
- Chlorophenothanum
- Chlorophenothanum technicum
- Chlorophenotoxum
- Chlorphenothan
- Chlorphenotoxum
- Citox
- Clofenotane
- Clofenotane technique
- Clofenotano
- Clofenotano [INN-Spanish]
- Clofenotanum
- Clofenotanum [INN-Latin]
- D.D.T. technique
- DDT
- DDT 50 WP
- Deoval
- Detox
- Detox (pesticide)
- Detoxan
- Dibovin
- Dicophane
- Didigam
- Didimac
- Dodat
- Dykol
- EINECS 200-024-3
- ENT 1,506
- EPA Pesticide Chemical Code 029201
- Estonate
- Ethane, 1,1,1-trichloro-2,2-bis(4-chlorophenyl)-
- Ethane, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-
- Genitox
- Gesafid
- Gesarol
- Guesarol
- Gyron
- Hildit
- HSDB 200
- Ivoran
- Ixodex
- Klorfenoton
- Klorfenoton [Swedish Pharmacopoeia]
- Kopsol
- Mutoxan
- NCI-C00464
- Neocid
- Neocid (VAN)
- Neocidol
- Neocidol (solid)
- NSC 8939
- OMS 0016
- OMS 0016 [French]
- OMS 16
- p'-Zeidane
- p'-Zeidane [France]
- p,p'-DDT
- p,p'-Dichlorodiphenyltrichloroethane
- Parachlorocidum
- PEB1
- Pentachlorin
- Pentech
- Penticidum
- RCRA waste number U061
- Rukseam
- Santobane
- Tafidex
- Trichlorobis(4-chlorophenyl)ethane
- UNII-CIW5S16655
- Zerdane
Systematic Names
- 1,1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane
- Benzene, 1,1'-(2,2,2-trichloroethylidene)bis(4-chloro-
- Clofenotane
- Ethane, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-
- p,p'-DDT
Superlist Names
- 4,4'-DDT
- Benzene, 1,1'-(2,2,2-trichloroethylidene)bis(4-chloro-
- DDT
- DDT and metabolites
- DDT, p,p'-
- Dichlorodiphenyltrichloroethane
- p,p'-DDT
- RCRA waste no. U061
Registry Numbers
CAS Registry Number
- 50-29-3
FDA UNII
- CIW5S16655
Other Registry Number
- 1081843-15-3
System Generated Number
- 0000050293
Structure Descriptors
InChI
InChI=1S/C14H9Cl5/c15-11-5-1-9(2-6-11)13(14(17,18)19)10-3-7-12(16)8-4-10/h1-8,13HInChIKey
YVGGHNCTFXOJCH-UHFFFAOYSA-NSmiles
Clc1ccc(cc1)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LDLo | intravenous | 40mg/kg (40mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: EXCITEMENT BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 213, 1946. |
cat | LDLo | oral | 250mg/kg (250mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: TREMOR BEHAVIORAL: EXCITEMENT | Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 213, 1946. |
chicken | LDLo | oral | 300mg/kg (300mg/kg) | Medizinische Monatsschrift. Vol. 4, Pg. 25, 1950. | |
dog | LD50 | oral | 150mg/kg (150mg/kg) | Yakkyoku. Pharmacy. Vol. 32, Pg. 463, 1981. | |
dog | LDLo | intravenous | 75mg/kg (75mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: TREMOR | Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 213, 1946. |
domestic animals - goat/sheep | LDLo | oral | 300mg/kg (300mg/kg) | Medizinische Monatsschrift. Vol. 4, Pg. 25, 1950. | |
frog | LD50 | oral | 7600ug/kg (7.6mg/kg) | Environmental Pollution. Vol. 20, Pg. 45, 1979. | |
frog | LD50 | parenteral | 24100ug/kg (24.1mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 74, Pg. 343, 1947. | |
guinea pig | LD50 | oral | 150mg/kg (150mg/kg) | European Journal of Toxicology and Environmental Hygiene. Vol. 7, Pg. 159, 1974. | |
guinea pig | LD50 | skin | 1gm/kg (1000mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA | British Medical Journal. Vol. 1, Pg. 865, 1945. |
guinea pig | LD50 | subcutaneous | 900mg/kg (900mg/kg) | BEHAVIORAL: ATAXIA BEHAVIORAL: TREMOR BEHAVIORAL: MUSCLE WEAKNESS | British Medical Journal. Vol. 1, Pg. 865, 1945. |
hamster | LD50 | oral | > 5gm/kg (5000mg/kg) | Laboratory Animal Science. Vol. 26, Pg. 274, 1976. | |
human | LDLo | oral | 500mg/kg (500mg/kg) | CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 446, 1989. |
human | TDLo | oral | 5mg/kg (5mg/kg) | BEHAVIORAL: ANALGESIA BEHAVIORAL: GENERAL ANESTHETIC | Pharmazie. Vol. 2, Pg. 268, 1947. |
human | TDLo | oral | 16mg/kg (16mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | "Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public Health Service, Communicable Disease Center, Atlanta, GA, 1956Vol. -, Pg. 1, 1956. |
infant | LDLo | oral | 150mg/kg (150mg/kg) | LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA | British Medical Journal. Vol. 2, Pg. 845, 1945. |
mammal (species unspecified) | LD50 | unreported | 200mg/kg (200mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 17(3), Pg. 32, 1973. | |
man | LDLo | unreported | 221mg/kg (221mg/kg) | "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970. | |
man | TDLo | oral | 6mg/kg (6mg/kg) | GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: HEADACHE SKIN AND APPENDAGES (SKIN): SWEATING: OTHER | "Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public Health Service, Communicable Disease Center, Atlanta, GA, 1956Vol. -, Pg. 1, 1956. |
monkey | LD50 | oral | 200mg/kg (200mg/kg) | Advances in Pharmacology and Chemotherapy. Vol. 12, Pg. 31, 1975. | |
monkey | LDLo | intravenous | 50mg/kg (50mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: TREMOR | Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 213, 1946. |
mouse | LD50 | intraperitoneal | 32mg/kg (32mg/kg) | Proceedings of the European Society of Toxicology. Vol. 17, Pg. 351, 1976. | |
mouse | LD50 | oral | 135mg/kg (135mg/kg) | Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 12, Pg. 368, 1953. | |
rabbit | LD50 | oral | 250mg/kg (250mg/kg) | Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 347, 1966. | |
rabbit | LD50 | skin | 300mg/kg (300mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA | British Medical Journal. Vol. 1, Pg. 865, 1945. |
rabbit | LD50 | subcutaneous | 250mg/kg (250mg/kg) | BEHAVIORAL: ATAXIA BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: TREMOR | British Medical Journal. Vol. 1, Pg. 865, 1945. |
rabbit | LDLo | intravenous | 50mg/kg (50mg/kg) | BEHAVIORAL: EXCITEMENT BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 213, 1946. |
rat | LD50 | intraperitoneal | 9100ug/kg (9.1mg/kg) | Proceedings of the European Society of Toxicology. Vol. 17, Pg. 351, 1976. | |
rat | LD50 | oral | 87mg/kg (87mg/kg) | Down to Earth. Vol. 35, Pg. 25, 1979. | |
rat | LD50 | skin | 1931mg/kg (1931mg/kg) | Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 14, 1978. | |
rat | LD50 | subcutaneous | 1500mg/kg (1500mg/kg) | BEHAVIORAL: ATAXIA BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: TREMOR | British Medical Journal. Vol. 1, Pg. 865, 1945. |
rat | LD50 | unreported | 300mg/kg (300mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 37(10), Pg. 27, 1972. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 108.5 | deg C | EXP | |
log P (octanol-water) | 6.91 | (none) | EXP | |
Water Solubility | 0.0055 | mg/L | 25 | EXP |
Vapor Pressure | 1.60E-07 | mm Hg | 20 | EXP |
Henry's Law Constant | 8.32E-06 | atm-m3/mole | 25 | EXP |
Atmospheric OH Rate Constant | 3.44E-12 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.