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Substance Name: DDT [BSI:ISO]
RN: 50-29-3
UNII: CIW5S16655
InChIKey: YVGGHNCTFXOJCH-UHFFFAOYSA-N

Note

  • A polychlorinated pesticide that is resistant to destruction by light and oxidation. Its unusual stability has resulted in difficulties in residue removal from water, soil, and foodstuffs. This substance may reasonably be anticipated to be a carcinogen: Fourth Annual Report on Carcinogens (NTP-85-002, 1985). (From Merck Index, 11th ed)

Molecular Formula

  • C14-H9-Cl5

Molecular Weight

  • 354.4901
 

Classification Codes

Classification Codes

  • Agricultural Chemical
  • Human Data
  • Insecticide
  • Mutation Data
  • Reproductive Effect
  • TSCA Flag S (Substance is Identified in a Proposed or Final SNUR (Significant New Use Rule) under TSCA)
  • Tumor Data

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 12
  • 2011 CERCLA Priority List, Rank: 13
  • Overall Carcinogenic Evaluation: Group 2B
  • Reasonably Anticipated to be a Carcinogen
  • Reportable Quantity (RQ) = 1 lb
  • TWA 1 mg/m3; Confirmed animal carcinogen with unknown relevance to humans
  • TWA 1 mg/m3; skin

Names and Synonyms

Results Name

  • DDT [BSI:ISO]

Name of Substance

  • Chlorophenothane [NF]
  • Clofenotane [INN]
  • DDT
  • DDT [BSI:ISO]

MeSH Heading

  • DDT

Synonyms

  • 1,1'-(2,2,2-Trichloroethylidene)bis(4-chlorobenzene)
  • 1,1,1-Trichloor-2,2-bis(4-chloor fenyl)-ethaan
  • 1,1,1-Trichloor-2,2-bis(4-chloor fenyl)-ethaan [Dutch]
  • 1,1,1-Trichlor-2,2-bis(4-chlor-phenyl)-aethan
  • 1,1,1-Trichlor-2,2-bis(4-chlor-phenyl)-aethan [German]
  • 1,1,1-Trichloro-2,2-bis(4,4'-dichlorodiphenyl)ethane
  • 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane
  • 1,1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane
  • 1,1,1-Trichloro-2,2-di(4-chlorophenyl)-ethane
  • 1,1,1-Tricloro-2,2-bis(4-cloro-fenil)-etano
  • 1,1,1-Tricloro-2,2-bis(4-cloro-fenil)-etano [Italian]
  • 1,1,1-Tricloro-2,2-bis(4-cloro-fenyl)-etano
  • 1,1,1-Tricloro-2,2-bis(4-cloro-fenyl)-etano [Italian]
  • 1,1-Bis-(p-chlorophenyl)-2,2,2-trichloroethane
  • 2,2-Bis(p-chlorophenyl)-1,1,1-trichloroethane
  • 4,4'-DDT
  • 4,4'-Dichlorodiphenyltrichloroethane
  • 4-05-00-01885 (Beilstein Handbook Reference)
  • Aavero-extra
  • Agritan
  • AI3-01506
  • alpha,alpha-Bis(p-chlorophenyl)-beta,beta,beta-trichloroethane
  • Anofex
  • Arkotine
  • Azotox M 33
  • Benzochloryl
  • Bosan Supra
  • Bovidermol
  • BRN 1882657
  • Caswell No. 308
  • CCRIS 194
  • Chlofenotan
  • Chlorophenothan
  • Chlorophenothane
  • Chlorophenothanum
  • Chlorophenothanum technicum
  • Chlorophenotoxum
  • Chlorphenothan
  • Chlorphenotoxum
  • Citox
  • Clofenotane
  • Clofenotane technique
  • Clofenotano
  • Clofenotano [INN-Spanish]
  • Clofenotanum
  • Clofenotanum [INN-Latin]
  • D.D.T. technique
  • DDT
  • DDT 50 WP
  • Deoval
  • Detox
  • Detox (pesticide)
  • Detoxan
  • Dibovin
  • Dicophane
  • Didigam
  • Didimac
  • Dodat
  • Dykol
  • EINECS 200-024-3
  • ENT 1,506
  • EPA Pesticide Chemical Code 029201
  • Estonate
  • Ethane, 1,1,1-trichloro-2,2-bis(4-chlorophenyl)-
  • Ethane, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-
  • Genitox
  • Gesafid
  • Gesarol
  • Guesarol
  • Gyron
  • Hildit
  • HSDB 200
  • Ivoran
  • Ixodex
  • Klorfenoton
  • Klorfenoton [Swedish Pharmacopoeia]
  • Kopsol
  • Mutoxan
  • NCI-C00464
  • Neocid
  • Neocid (VAN)
  • Neocidol
  • Neocidol (solid)
  • NSC 8939
  • OMS 0016
  • OMS 0016 [French]
  • OMS 16
  • p'-Zeidane
  • p'-Zeidane [France]
  • p,p'-DDT
  • p,p'-Dichlorodiphenyltrichloroethane
  • Parachlorocidum
  • PEB1
  • Pentachlorin
  • Pentech
  • Penticidum
  • RCRA waste number U061
  • Rukseam
  • Santobane
  • Tafidex
  • Trichlorobis(4-chlorophenyl)ethane
  • UNII-CIW5S16655
  • Zerdane

Systematic Names

  • 1,1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane
  • Benzene, 1,1'-(2,2,2-trichloroethylidene)bis(4-chloro-
  • Clofenotane
  • Ethane, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-
  • p,p'-DDT

Superlist Names

  • 4,4'-DDT
  • Benzene, 1,1'-(2,2,2-trichloroethylidene)bis(4-chloro-
  • DDT
  • DDT and metabolites
  • DDT, p,p'-
  • Dichlorodiphenyltrichloroethane
  • p,p'-DDT
  • RCRA waste no. U061

Registry Numbers

CAS Registry Number

  • 50-29-3

FDA UNII

  • CIW5S16655

Other Registry Number

  • 1081843-15-3

System Generated Number

  • 0000050293

Structure Descriptors

InChI

1S/C14H9Cl5/c15-11-5-1-9(2-6-11)13(14(17,18)19)10-3-7-12(16)8-4-10/h1-8,13H

InChIKey

YVGGHNCTFXOJCH-UHFFFAOYSA-N

Smiles

c1cc(ccc1C(c2ccc(cc2)Cl)C(Cl)(Cl)Cl)Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intravenous 40mg/kg (40mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: EXCITEMENT

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 213, 1946.
cat LDLo oral 250mg/kg (250mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: TREMOR

BEHAVIORAL: EXCITEMENT
Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 213, 1946.
chicken LDLo oral 300mg/kg (300mg/kg)   Medizinische Monatsschrift. Vol. 4, Pg. 25, 1950.
dog LD50 oral 150mg/kg (150mg/kg)   Yakkyoku. Pharmacy. Vol. 32, Pg. 463, 1981.
dog LDLo intravenous 75mg/kg (75mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: TREMOR
Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 213, 1946.
domestic animals - goat/sheep LDLo oral 300mg/kg (300mg/kg)   Medizinische Monatsschrift. Vol. 4, Pg. 25, 1950.
frog LD50 oral 7600ug/kg (7.6mg/kg)   Environmental Pollution. Vol. 20, Pg. 45, 1979.
frog LD50 parenteral 24100ug/kg (24.1mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 74, Pg. 343, 1947.
guinea pig LD50 oral 150mg/kg (150mg/kg)   European Journal of Toxicology and Environmental Hygiene. Vol. 7, Pg. 159, 1974.
guinea pig LD50 skin 1gm/kg (1000mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: ATAXIA
British Medical Journal. Vol. 1, Pg. 865, 1945.
guinea pig LD50 subcutaneous 900mg/kg (900mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: TREMOR

BEHAVIORAL: MUSCLE WEAKNESS
British Medical Journal. Vol. 1, Pg. 865, 1945.
hamster LD50 oral > 5gm/kg (5000mg/kg)   Laboratory Animal Science. Vol. 26, Pg. 274, 1976.
human LDLo oral 500mg/kg (500mg/kg) CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
"Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 446, 1989.
human TDLo oral 5mg/kg (5mg/kg) BEHAVIORAL: ANALGESIA

BEHAVIORAL: GENERAL ANESTHETIC
Pharmazie. Vol. 2, Pg. 268, 1947.
human TDLo oral 16mg/kg (16mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD "Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public Health Service, Communicable Disease Center, Atlanta, GA, 1956Vol. -, Pg. 1, 1956.
infant LDLo oral 150mg/kg (150mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA British Medical Journal. Vol. 2, Pg. 845, 1945.
mammal (species unspecified) LD50 unreported 200mg/kg (200mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 17(3), Pg. 32, 1973.
man LDLo unreported 221mg/kg (221mg/kg)   "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
man TDLo oral 6mg/kg (6mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

BEHAVIORAL: HEADACHE

SKIN AND APPENDAGES (SKIN): SWEATING: OTHER
"Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public Health Service, Communicable Disease Center, Atlanta, GA, 1956Vol. -, Pg. 1, 1956.
monkey LD50 oral 200mg/kg (200mg/kg)   Advances in Pharmacology and Chemotherapy. Vol. 12, Pg. 31, 1975.
monkey LDLo intravenous 50mg/kg (50mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: TREMOR
Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 213, 1946.
mouse LD50 intraperitoneal 32mg/kg (32mg/kg)   Proceedings of the European Society of Toxicology. Vol. 17, Pg. 351, 1976.
mouse LD50 oral 135mg/kg (135mg/kg)   Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 12, Pg. 368, 1953.
rabbit LD50 oral 250mg/kg (250mg/kg)   Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 347, 1966.
rabbit LD50 skin 300mg/kg (300mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: ATAXIA
British Medical Journal. Vol. 1, Pg. 865, 1945.
rabbit LD50 subcutaneous 250mg/kg (250mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: TREMOR
British Medical Journal. Vol. 1, Pg. 865, 1945.
rabbit LDLo intravenous 50mg/kg (50mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 213, 1946.
rat LD50 intraperitoneal 9100ug/kg (9.1mg/kg)   Proceedings of the European Society of Toxicology. Vol. 17, Pg. 351, 1976.
rat LD50 oral 87mg/kg (87mg/kg)   Down to Earth. Vol. 35, Pg. 25, 1979.
rat LD50 skin 1931mg/kg (1931mg/kg)   Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 14, 1978.
rat LD50 subcutaneous 1500mg/kg (1500mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: TREMOR
British Medical Journal. Vol. 1, Pg. 865, 1945.
rat LD50 unreported 300mg/kg (300mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 37(10), Pg. 27, 1972.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 108.5 deg C   EXP
log P (octanol-water) 6.91 (none)   EXP
Water Solubility 0.0055 mg/L 25 EXP
Vapor Pressure 1.60E-07 mm Hg 20 EXP
Henry's Law Constant 8.32E-06 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 3.44E-12 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.