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Substance Name: Lypressin [USAN:USP:INN:BAN]
RN: 50-57-7
UNII: 7CZF3L922Y
InChIKey: BJFIDCADFRDPIO-DZCXQCEKSA-N

Note

  • The porcine antidiuretic hormone (VASOPRESSINS). It is a cyclic nonapeptide that differs from ARG-VASOPRESSIN by one amino acid, containing a LYSINE at residue 8 instead of an ARGININE. Lys-vasopressin is used to treat DIABETES INSIPIDUS or to improve vasomotor tone and BLOOD PRESSURE.

Molecular Formula

  • C46-H65-N13-O12-S2

Molecular Weight

  • 1056.2305
 

Classification Codes

  • Antidiuretic
  • Antidiuretic Agents
  • Cardiovascular Agents
  • Coagulants
  • Drug / Therapeutic Agent
  • Hematologic Agents
  • Hemostatics
  • Natriuretic Agents
  • Reproductive Effect
  • Vasoconstrictor
  • Vasoconstrictor Agents
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Names and Synonyms

Results Name

  • Lypressin [USAN:USP:INN:BAN]

Name of Substance

  • Lypressin [USAN:USP:INN:BAN]
  • Vasopressin (lysine form)

MeSH Heading

  • Lypressin

Synonyms

  • (8-Lysine)vasopressin
  • 8-L-Lysine vasopressin
  • 8-L-Lysinevasopressin
  • BRN 4648365
  • Diapid
  • EINECS 200-050-5
  • L-8
  • L-Cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysylglycinamide cyclic (1-6)-disulfide
  • L-Cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysylglycinamide cyclic (1->6)-disulfide
  • L-Lysine vasopressin
  • Lipresina
  • Lipresina [INN-Spanish]
  • Lipressina
  • Lipressina [DCIT]
  • Lypressin
  • Lypressine
  • Lypressine [INN-French]
  • Lypressinum
  • Lypressinum [INN-Latin]
  • Lysine pitressin
  • Lysine vasopressin
  • Lysine-vasopressin
  • Pitressin
  • Postacton
  • Syntopressin
  • UNII-7CZF3L922Y
  • Vasophysin
  • Vasopressin-8-lysine

Systematic Names

  • Lypressin
  • Vasopressin, 8-L-lysine-

Registry Numbers

CAS Registry Number

  • 50-57-7

FDA UNII

  • 7CZF3L922Y

System Generated Number

  • 0000050577

Structure Descriptors

InChI

1S/C46H65N13O12S2/c47-17-5-4-9-29(40(65)52-22-38(51)63)54-45(70)35-10-6-18-59(35)46(71)34-24-73-72-23-28(48)39(64)55-31(20-26-11-13-27(60)14-12-26)43(68)56-32(19-25-7-2-1-3-8-25)42(67)53-30(15-16-36(49)61)41(66)57-33(21-37(50)62)44(69)58-34/h1-3,7-8,11-14,28-35,60H,4-6,9-10,15-24,47-48H2,(H2,49,61)(H2,50,62)(H2,51,63)(H,52,65)(H,53,67)(H,54,70)(H,55,64)(H,56,68)(H,57,66)(H,58,69)/t28-,29-,30-,31-,32-,33-,34-,35-/m0/s1

InChIKey

BJFIDCADFRDPIO-DZCXQCEKSA-N

Smiles

NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]2CSSC[C@H](N)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@@H](Cc4ccccc4)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N2)C(=O)NCC(=O)N