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Substance Name: Apixaban [USAN:INN:JAN]
RN: 503612-47-3
UNII: 3Z9Y7UWC1J
InChIKey: QNZCBYKSOIHPEH-UHFFFAOYSA-N

Notes

  • An antithrombotic agent.
  • An antithrombotic agent.

    DailyMed: ELIQUIS is a factor Xa inhibitor anticoagulant indicated:
    -- to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation.
    -- for the prophylaxis of deep vein thrombosis (DVT), which may lead to pulmonary embolism (PE), in patients who have undergone hip or knee replacement surgery.

Molecular Formula

  • C25-H25-N5-O4

Molecular Weight

  • 459.5035
 

Classification Codes

  • Anticoagulant, Antithrombotic
  • Anticoagulants
  • Antithrombins
  • Enzyme Inhibitors
  • Factor Xa Inhibitors
  • Hematologic Agents
  • Protease Inhibitors
  • Serine Proteinase Inhibitors

Names and Synonyms

Name of Substance

  • Apixaban
  • Apixaban [USAN:INN:JAN]

Synonyms

  • 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo(3,4c)pyridine-3-carboxamide
  • Apixaban
  • BMS 562247-01
  • BMS-562247-01
  • Eliquis
  • HSDB 8223
  • UNII-3Z9Y7UWC1J

Systematic Name

  • 1H-Pyrazolo(3,4-c)pyridine-3-carboxamide,4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxo-1-piperidinyl)phenyl)-

Registry Numbers

CAS Registry Number

  • 503612-47-3

FDA UNII

  • 3Z9Y7UWC1J

System Generated Number

  • 0503612473

Structure Descriptors

InChI

1S/C25H25N5O4/c1-34-19-11-9-18(10-12-19)30-23-20(22(27-30)24(26)32)13-15-29(25(23)33)17-7-5-16(6-8-17)28-14-3-2-4-21(28)31/h5-12H,2-4,13-15H2,1H3,(H2,26,32)

InChIKey

QNZCBYKSOIHPEH-UHFFFAOYSA-N

Smiles

N1(CCc2c(C1=O)n(nc2C(=O)N)c1ccc(cc1)OC)c1ccc(cc1)N1CCCCC1=O