Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Tolnidamine [INN]
RN: 50454-68-7
UNII: Z5M7SC6D5P
InChIKey: IWKDFIXLGQOEKD-UHFFFAOYSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Reproductive Effect

Molecular Formula

  • C16-H13-Cl-N2-O2

Molecular Weight

  • 300.744
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Tolnidamine
  • Tolnidamine [INN]

Synonyms

  • 1-((2-Methyl-4-chlorophenyl)methyl)-indazole-3-carboxylic acid
  • 1-((4-Chloro-2-methylphenyl)methyl)-1H-indazole-3-carboxylic acid
  • 1-(4-Chloro-2-methylbenzyl)-1H-indazole-3-carboxylic acid
  • 1b, Indazole
  • 1H-Indazole-3-carboxylic acid, 1-((2-methyl-4-chlorophenyl)methyl)-
  • 1H-Indazole-3-carboxylic acid, 1-((4-chloro-2-methylphenyl)methyl)-
  • 5-25-04-00250 (Beilstein Handbook Reference)
  • AF 1923
  • BRN 0893287
  • NSC 283448
  • Tolnidamide
  • Tolnidamine
  • Tolnidamino
  • Tolnidamino [INN-Spanish]
  • Tolnidaminum
  • Tolnidaminum [INN-Latin]
  • UNII-Z5M7SC6D5P

Systematic Names

  • 1-(4-Chloro-2-methylbenzyl)-1H-indazole-3-carboxylic acid
  • 1H-Indazole-3-carboxylic acid, 1-(4-chloro-2-methylbenzyl)-

Registry Numbers

CAS Registry Number

  • 50454-68-7

FDA UNII

  • Z5M7SC6D5P

System Generated Number

  • 0050454687

Structure Descriptors

InChI

1S/C16H13ClN2O2/c1-10-8-12(17)7-6-11(10)9-19-14-5-3-2-4-13(14)15(18-19)16(20)21/h2-8H,9H2,1H3,(H,20,21)

InChIKey

IWKDFIXLGQOEKD-UHFFFAOYSA-N

Smiles

c1(C(O)=O)nn(Cc2ccc(cc2C)Cl)c2c1cccc2

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 575mg/kg (575mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Chemotherapy Vol. 27(Suppl,
mouse LD50 oral 1250mg/kg (1250mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Chemotherapy Vol. 27(Suppl,
rat LD50 intraperitoneal 1120mg/kg (1120mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Chemotherapy Vol. 27(Suppl,
rat LD50 oral 4gm/kg (4000mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Chemotherapy Vol. 27(Suppl,