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Substance Name: Tetramisole hydrochloride [USAN]
RN: 5086-74-8
UNII: 0NDK265MCV
InChIKey: LAZPBGZRMVRFKY-UHFFFAOYSA-N

Classification Codes

  • Anthelmintic
  • Human Data

Molecular Formula

  • C11-H12-N2-S.Cl-H

Molecular Weight

  • 240.7567
 
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Names and Synonyms

Name of Substance

  • Tetramisole hydrochloride
  • Tetramisole hydrochloride [USAN]

Synonyms

  • (+-)-2,3,5,6-Tetrahydro-6-phenylimidazo(2,1-b)thiazole monohydrochloride
  • Anthelvet
  • Ascarotrat
  • Bayer 9051
  • Citarin
  • Citarin (VAN)
  • Concurat
  • DL-6-Phenyl-2,3,5,6-tetrahydroimidazole(2,1-b)thiazole-hydrochloride
  • EINECS 225-799-5
  • Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (+-)-
  • McN JR 8299
  • McN-JR-8299
  • McN-JR-8299-11
  • Nilverm
  • Nilverom
  • NSC 170985
  • Orovermol
  • Pig Wormer
  • R 8299
  • Ripercol
  • Solaskil hydrochloride
  • Spartakon
  • Tetramisole HCl
  • Tetramisole hydrochloride
  • UNII-0NDK265MCV

Systematic Names

  • Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (+-)-
  • Tetramisole hydrochloride

Registry Numbers

CAS Registry Number

  • 5086-74-8

FDA UNII

  • 0NDK265MCV

System Generated Number

  • 0005086748

Molecular Formulas

Molecular Formula

  • C11-H12-N2-S.Cl-H

Molecular Formula Fragments

  • C11-H12-N2-S
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H

InChIKey

LAZPBGZRMVRFKY-UHFFFAOYSA-N

Smiles

c1ccc(cc1)C2CN3CCSC3=N2.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
duck LD50 oral 958mg/kg (958mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) Veterinariya. Veterinary Science. Vol. 54(5), Pg. 64, 1978.
human TDLo oral 2mg/kg (2mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Toxicology and Applied Pharmacology. Vol. 20, Pg. 602, 1971.
mouse LD50 intravenous 22mg/kg (22mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Nature. Vol. 209, Pg. 1084, 1966.
mouse LD50 oral 210mg/kg (210mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Nature. Vol. 209, Pg. 1084, 1966.
mouse LD50 subcutaneous 84mg/kg (84mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Nature. Vol. 209, Pg. 1084, 1966.
rat LD50 intravenous 24mg/kg (24mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Nature. Vol. 209, Pg. 1084, 1966.
rat LD50 oral 480mg/kg (480mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Nature. Vol. 209, Pg. 1084, 1966.
rat LD50 subcutaneous 130mg/kg (130mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Nature. Vol. 209, Pg. 1084, 1966.