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Substance Name: Idursulfase [USAN:INN:BAN:JAN]
RN: 50936-59-9
UNII: 5W8JGG2651


  • An enzyme that specifically cleaves the ester sulfate of iduronic acid. Its deficiency has been demonstrated in Hunter's syndrome, which is characterized by an excess of dermatan sulfate and heparan sulfate.

Molecular Formula

  • C2689-H4057-N699-O792-S14

Classification Codes

  • Enzyme that Degrades the Glycosaminoglycans Heparan Sulfate and Dermatan Sulfate
  • Treatment of Hunter Syndrome (Enzyme that Degrades the Glycosaminoglycans Heparan Sulfate and Dermatan Sulfate)

Names and Synonyms

Name of Substance

  • Idursulfase [USAN:INN:BAN:JAN]

MeSH Heading

  • Iduronate Sulfatase


  • 2-Sulfo-L-iduronate 2-sulfatase
  • alpha-L-Iduronate sulfate sulfatase
  • EC
  • Elaprase
  • Iduronade-2-sulfate sulfatase
  • Iduronate sulfate sulfatase
  • Iduronate-2-sulfatase
  • Iduronide-2-sulfate sulfatase
  • Idurono-2-sulfatase
  • Idursulfase
  • Idusulfase
  • Idusulfase [INN]
  • L-Iduronate 2-sulfate sulfatase
  • L-Idurono sulfate sulfatase
  • L-Iduronosulfatase
  • Sulfatase, L-idurono-
  • Sulfo-L-iduronate sulfatase
  • Sulfoiduronate sulfohydrolase
  • UNII-5W8JGG2651

Systematic Names

  • alpha-L-Iduronate sulfate sulfatase
  • Sulfatase, L-idurono-

Registry Numbers

CAS Registry Number

  • 50936-59-9


  • 5W8JGG2651

System Generated Number

  • 0050936599