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Substance Name: Idursulfase [USAN:INN:BAN:JAN]
RN: 50936-59-9
UNII: 5W8JGG2651


  • An enzyme that specifically cleaves the ester sulfate of iduronic acid. Its deficiency has been demonstrated in Hunter's syndrome, which is characterized by an excess of dermatan sulfate and heparan sulfate.
  • For treating Hunter syndrome.

Molecular Formula

  • C2689-H4057-N699-O792-S14

Classification Codes

  • Enzyme that Degrades the Glycosaminoglycans Heparan Sulfate and Dermatan Sulfate
  • Treatment of Hunter Syndrome (Enzyme that Degrades the Glycosaminoglycans Heparan Sulfate and Dermatan Sulfate)
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Links to Resources

Names and Synonyms

Name of Substance

  • Idursulfase [USAN:INN:BAN:JAN]

MeSH Heading

  • Iduronate Sulfatase


  • 2-Sulfo-L-iduronate 2-sulfatase
  • alpha-L-Iduronate sulfate sulfatase
  • EC
  • Elaprase
  • Iduronade-2-sulfate sulfatase
  • Iduronate sulfate sulfatase
  • Iduronate-2-sulfatase
  • Iduronide-2-sulfate sulfatase
  • Idurono-2-sulfatase
  • Idursulfase
  • Idusulfase
  • Idusulfase [INN]
  • L-Iduronate 2-sulfate sulfatase
  • L-Idurono sulfate sulfatase
  • L-Iduronosulfatase
  • Sulfatase, L-idurono-
  • Sulfo-L-iduronate sulfatase
  • Sulfoiduronate sulfohydrolase
  • UNII-5W8JGG2651

Systematic Names

  • alpha-L-Iduronate sulfate sulfatase
  • Sulfatase, L-idurono-

Registry Numbers

CAS Registry Number

  • 50936-59-9


  • 5W8JGG2651

System Generated Number

  • 0050936599