Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Norepinephrine bitartrate
RN: 51-40-1
UNII: ZW81GF408B
InChIKey: WNPNNLQNNJQYFA-YIDNRZKSSA-N

Note

  • Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.

Molecular Formula

  • C8-H11-N-O3.C4-H6-O6

Molecular Weight

  • 319.2643
 

Classification Codes

  • Drug / Therapeutic Agent
  • Mutation Data
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Results Name

  • Norepinephrine bitartrate

Name of Substance

  • Norepinephrine bitartrate anhydrous

Synonyms

  • (-)-Noradrenaline (+)-bitartrate
  • (-)-Norepinephrine bitartrate
  • (-)-R-Norepinephrine bitartrate
  • Arterenol bitartrate
  • EINECS 200-095-0
  • l-Arterenol bitartrate
  • l-Arterenol d-bitartrate
  • L-Noradrenaline bitartrate
  • l-Noradrenaline d-bitartrate
  • l-Noradrenaline tartrate
  • l-Norepinephrine bitartrate
  • Levarterenol bitartrate
  • Levophed
  • Noradrenalin bitartrate
  • Noradrenalin bitartrate, l-
  • Noradrenaline acid tartrate
  • Noradrenaline bitartrate
  • Noradrenaline hydrogen tartrate
  • Noradrenaline tartrate
  • Noradrenaline, tartrate (1:1)
  • Norartrinal bitartrate
  • Norepinephrine
  • Norepinephrine tartrate
  • NSC 169106
  • UNII-ZW81GF408B

Systematic Names

  • 1,2-Benzenediol, 4-((1R)-2-amino-1-hydroxyethyl)-, (2R,3R)-2,3-dihydroxybutanedioate (1:1) (salt)
  • 1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (R)-, (R-(R*,R*))-2,3-dihydroxybutanedioate (1:1)
  • Benzyl alcohol, alpha-(aminomethyl)-3,4-dihydroxy-, (-)-, tartrate (1:1)
  • Benzyl alcohol, alpha-(aminomethyl)-3,4-dihydroxy-, (-)-, tartrate (1:1) (salt)
  • Norepinephrine hydrogen tartrate

Registry Numbers

CAS Registry Number

  • 51-40-1

FDA UNII

  • ZW81GF408B

Other Registry Numbers

  • 2477-42-1
  • 24868-01-7
  • 33404-26-1
  • 350-25-4
  • 73-98-3
  • 893-91-4

Related Registry Number

  • 51-41-2 (Parent)

System Generated Number

  • 0000051401

Molecular Formulas

Molecular Formula

  • C8-H11-N-O3.C4-H6-O6

Molecular Formula Fragments

  • C4-H6-O6
  • C8-H11-N-O3
  • COMPONENT

Structure Descriptors

InChI

1S/C8H11NO3.C4H6O6/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10)/t8-;1-,2-/m01/s1

InChIKey

WNPNNLQNNJQYFA-YIDNRZKSSA-N

Smiles

c1(c(cc(cc1)[C@H](CN)O)O)O.C(=O)([C@@H]([C@H](C(=O)O)O)O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 26800ug/kg (26.8mg/kg)   Dissertationes Pharmaceuticae et Pharmacologicae. Vol. 23, Pg. 435, 1971.
mouse LD50 intravenous 1025ug/kg (1.025mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
European Journal of Pharmacology. Vol. 9, Pg. 289, 1970.
rat LD50 intravenous 210ug/kg (0.21mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 7, Pg. 627, 1979.
rat LDLo subcutaneous 3987ug/kg (3.987mg/kg) BEHAVIORAL: EXCITEMENT Journal of Pharmacology and Experimental Therapeutics. Vol. 95, Pg. 155, 1949.