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Substance Name: Meclofenoxate [INN:BAN:DCF]
RN: 51-68-3
UNII: C76QQ2I0RG
InChIKey: XZTYGFHCIAKPGJ-UHFFFAOYSA-N

Note

  • An ester of DIMETHYLAMINOETHANOL and para-chlorophenoxyacetic acid.

Molecular Formula

  • C12-H16-Cl-N-O3

Molecular Weight

  • 257.7154
 

Classification Codes

  • Central Nervous System Agents
  • Drug / Therapeutic Agent
  • Neuroprotective Agents
  • Nootropic Agents
  • Protective Agents
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Names and Synonyms

Name of Substance

  • Meclofenoxate [INN:BAN:DCF]
  • Meclophenoxate

MeSH Heading

  • Meclofenoxate

Synonyms

  • 2-(Dimethylamino)ethyl (p-chlorophenoxy)acetate
  • Analux
  • ANP 235
  • BRN 1914094
  • Centrexin
  • Cerebon
  • Cetrexin
  • Clocete
  • Clofenoxin
  • Clopenoxin
  • Clophenoxate
  • Deanol p-chlorophenoxyacetate
  • Deanolestere
  • Dimethylaminoethyl-4-chlorophenoxyacetic acid
  • Dimethylaminoethyl-p-chlorophenoxyacetate
  • EINECS 200-116-3
  • EN 1627
  • Licidril
  • Mechlorphenoxatum
  • Meclofenossato
  • Meclofenossato [DCIT]
  • Meclofenoxate
  • Meclofenoxato
  • Meclofenoxato [INN-Spanish]
  • Meclofenoxatum
  • Meclofenoxatum [INN-Latin]
  • Meclophenoxate
  • Mucidril
  • NSC 169411
  • p-Chlorophenoxyacetic acid beta-dimethylaminoethyl ester
  • Proseryl
  • UNII-C76QQ2I0RG

Systematic Names

  • 2-(Dimethylamino)ethyl(p-chlorphenoxy)acetate
  • Acetic acid, (p-chlorophenoxy)-, 2-(dimethylamino)ethyl ester
  • Meclofenoxate

Registry Numbers

CAS Registry Number

  • 51-68-3

FDA UNII

  • C76QQ2I0RG

System Generated Number

  • 0000051683

Structure Descriptors

InChI

1S/C12H16ClNO3/c1-14(2)7-8-16-12(15)9-17-11-5-3-10(13)4-6-11/h3-6H,7-9H2,1-2H3

InChIKey

XZTYGFHCIAKPGJ-UHFFFAOYSA-N

Smiles

c1(ccc(Cl)cc1)OCC(OCCN(C)C)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 758mg/kg (758mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Farmakologiya i Toksikologiya Vol. 38, Pg. 154, 1975.
mouse LD50 oral 1750mg/kg (1750mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 386, 1972.
rabbit LD50 intravenous 150mg/kg (150mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 386, 1972.
rat LD50 oral 2600mg/kg (2600mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 386, 1972.

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) 1.960 (none)   EST
Atmospheric OH Rate Constant 8.91E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.