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Substance Name: Phenelzine [INN:BAN]
RN: 51-71-8
UNII: O408N561GF
InChIKey: RMUCZJUITONUFY-UHFFFAOYSA-N

Note

  • One of the MONOAMINE OXIDASE INHIBITORS used to treat DEPRESSION; PHOBIC DISORDERS; and PANIC.

Molecular Formula

  • C8-H12-N2

Molecular Weight

  • 136.197
 

Classification Codes

  • Antidepressive Agents
  • Central Nervous System Agents
  • Drug / Therapeutic Agent
  • Enzyme Inhibitors
  • Human Data
  • Monoamine Oxidase Inhibitors
  • Mutation Data
  • Psychotropic Drugs
  • Reproductive Effect

Names and Synonyms

Name of Substance

  • Phenelzine
  • Phenelzine [INN:BAN]

MeSH Heading

  • Phenelzine

Synonyms

  • 1-Hydrazino-2-phenylethane
  • 2-Phenylethylhydrazine
  • 4-15-00-01269 (Beilstein Handbook Reference)
  • beta-Phenylethylhydrazine
  • BRN 0742354
  • EINECS 200-117-9
  • Fenelzin
  • Fenelzina
  • Fenelzina [INN-Spanish]
  • Fenelzyna
  • Fenelzyna [Polish]
  • Fenelzyne
  • Fenelzyne [Polish]
  • HSDB 8127
  • Hydrazine, (2-phenylethyl)-
  • Nardelzine
  • Nardil
  • Phenelzine
  • Phenelzinum
  • Phenelzinum [INN-Latin]
  • Phenethylhydrazine
  • Stinerval
  • UNII-O408N561GF
  • W 1544-A
  • W1544

Systematic Names

  • Hydrazine, (2-phenylethyl)-
  • Hydrazine, phenethyl-
  • Phenelzine

Registry Numbers

CAS Registry Number

  • 51-71-8

FDA UNII

  • O408N561GF

System Generated Number

  • 0000051718

Structure Descriptors

InChI

1S/C8H12N2/c9-10-7-6-8-4-2-1-3-5-8/h1-5,10H,6-7,9H2

InChIKey

RMUCZJUITONUFY-UHFFFAOYSA-N

Smiles

c1(ccccc1)CCNN

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
child TDLo oral 7500ug/kg (7.5mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
American Journal of Diseases of Children. Vol. 130, Pg. 507, 1976.
mouse LD50 intraperitoneal 135mg/kg (135mg/kg)   Farmakologiya i Toksikologiya Vol. 32, Pg. 526, 1969.
mouse LD50 oral 130mg/kg (130mg/kg)   Biochemical Pharmacology. Vol. 17, Pg. 369, 1968.
mouse LD50 subcutaneous 122mg/kg (122mg/kg)   Farmakologiya i Toksikologiya Vol. 37, Pg. 651, 1974.
women LDLo oral 30mg/kg (30mg/kg) LIVER: FATTY LIVER DEGERATION

LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA
Journal of Analytical Toxicology. Vol. 19, Pg. 265, 1995.
women TDLo oral 39600ug/kg/44 (39.6mg/kg) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"

BEHAVIORAL: TOXIC PSYCHOSIS
Journal of Clinical Psychiatry. Vol. 48, Pg. 340, 1987.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point < 25 deg C   EXP
log P (octanol-water) 0.970 (none)   EST
Atmospheric OH Rate Constant 7.97E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.