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Substance Name: Diosgenin
RN: 512-04-9
UNII: K49P2K8WLX
InChIKey: WQLVFSAGQJTQCK-VKROHFNGSA-N
Note
- A spirostan found in DIOSCOREA and other plants. The 25S isomer is called yamogenin. Solasodine is a natural derivative formed by replacing the spiro-ring with a nitrogen, which can rearrange to SOLANINE.
Molecular Formula
- C27-H42-O3
Molecular Weight
- 414.6258
- All
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
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Names and Synonyms
Name of Substance
- Diosgenin
MeSH Heading
- Diosgenin
Synonyms
- 22alpha-Spirost-5-en-3beta-ol
- 5-19-03-00030 (Beilstein Handbook Reference)
- BRN 0094582
- CCRIS 6803
- Diosgenin
- EINECS 208-134-3
- Nitogenin
- NSC 33396
- SP 37
- UNII-K49P2K8WLX
Systematic Names
- (20R,25R)-Spirost-5-en-3beta-ol
- Diosgenin
- Spirost-5-en-3-beta-ol, (25R)-
- Spirost-5-en-3-ol, (3beta,25R)- (9CI)
- Spirost-5-en-3beta-ol, (25R)- (8CI)
Registry Numbers
CAS Registry Number
- 512-04-9
FDA UNII
- K49P2K8WLX
System Generated Number
- 0000512049
Structure Descriptors
InChI
InChI=1S/C27H42O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1InChIKey
WQLVFSAGQJTQCK-VKROHFNGSA-NSmiles
C[C@@H]1CC[C@@]2(OC1)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 3564mg/kg (3564mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Pharmaceutical Chemistry Journal Vol. 11, Pg. 1095, 1977. |
mouse | LD50 | oral | > 8gm/kg (8000mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Pharmaceutical Chemistry Journal Vol. 11, Pg. 1095, 1977. |
rat | LD50 | intraperitoneal | 4872mg/kg (4872mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Pharmaceutical Chemistry Journal Vol. 11, Pg. 1095, 1977. |
rat | LD50 | oral | > 8gm/kg (8000mg/kg) | Pharmaceutical Chemistry Journal Vol. 11, Pg. 1095, 1977. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 205.5 | deg C | EXP | |
log P (octanol-water) | 6.340 | (none) | EST | |
Water Solubility | 0.02 | mg/L | 25 | EXP |
Atmospheric OH Rate Constant | 1.51E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.