Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Tiamenidine hydrochloride [USAN]
RN: 51274-83-0
UNII: 9SE2T8DW90
InChIKey: RPZYVGSSBVNVCS-UHFFFAOYSA-N

Classification Codes

  • Antihypertensive
  • Drug / Therapeutic Agent

Molecular Formula

  • C8-H10-Cl-N3-S.Cl-H

Molecular Weight

  • 252.168
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Tiamenidine hydrochloride
  • Tiamenidine hydrochloride [USAN]

Synonyms

  • 2-((2-Chloro-4-methyl-3-thienyl)amino)-2-imidazoline hydrochloride
  • 2-((2-Chloro-4-methyl-3-thienyl)amino)-2-imidazoline monohydrochloride
  • 2-(2'-Chloro-4'-methyl-3'-thienylamino)-1,3-diazacyclo-pent-2-ene hydrochloride
  • EINECS 257-100-4
  • HOE 42-440
  • HOE 440
  • N-(2-Chloro-4-methyl-3-thienyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride
  • Sundralen
  • Symcor
  • Thiamenidine hydrochloride
  • Tiamenidine
  • Tiamenidine HCl
  • Tiamenidine hydrochloride
  • UNII-9SE2T8DW90

Systematic Names

  • 1H-Imidazol-2-amine, N-(2-chloro-4-methyl-3-thienyl)-4,5-dihydro-, monohydrochloride
  • 2-Imidazoline, 2-((2-chloro-4-methyl-3-thienyl)amino)-, monohydrochloride
  • N-(2-Chloro-4-methyl-3-thienyl)-4,5-dihydro-1H-imidazol-2-amine monohydrochloride

Mixture Name

  • Symcorad

Registry Numbers

CAS Registry Number

  • 51274-83-0

FDA UNII

  • 9SE2T8DW90

Other Registry Numbers

  • 31428-62-3
  • 54405-23-1
  • 77262-32-9

Related Registry Number

  • 31428-61-2 (Parent)

System Generated Number

  • 0051274830

Molecular Formulas

Molecular Formula

  • C8-H10-Cl-N3-S.Cl-H

Molecular Formula Fragments

  • C8-H10-Cl-N3-S
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C8H10ClN3S.ClH/c1-5-4-13-7(9)6(5)12-8-10-2-3-11-8;/h4H,2-3H2,1H3,(H2,10,11,12);1H

InChIKey

RPZYVGSSBVNVCS-UHFFFAOYSA-N

Smiles

c1(c(csc1Cl)C)NC=1NCCN1.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 45mg/kg (45mg/kg) SKIN AND APPENDAGES (SKIN): HAIR: OTHER

AUTONOMIC NERVOUS SYSTEM: SYMPATHOMIMETIC

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 211, Pg. 305, 1974.
mouse LD50 oral 400mg/kg (400mg/kg) AUTONOMIC NERVOUS SYSTEM: SYMPATHOMIMETIC

SKIN AND APPENDAGES (SKIN): HAIR: OTHER

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 211, Pg. 305, 1974.
mouse LD50 subcutaneous 170mg/kg (170mg/kg) SKIN AND APPENDAGES (SKIN): HAIR: OTHER

AUTONOMIC NERVOUS SYSTEM: SYMPATHOMIMETIC

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 211, Pg. 305, 1974.
rat LD50 intravenous 40mg/kg (40mg/kg) SKIN AND APPENDAGES (SKIN): HAIR: OTHER

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

AUTONOMIC NERVOUS SYSTEM: SYMPATHOMIMETIC
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 211, Pg. 305, 1974.