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Substance Name: Tarenflurbil [USAN:INN]
RN: 51543-40-9
UNII: 501W00OOWA
InChIKey: SYTBZMRGLBWNTM-SNVBAGLBSA-N

Note

  • R-enantiomer of flurbiprofen but not a COX inhibitor; modulates NF-kB, gamma-secretase, amyloid beta-protein.

Molecular Formula

  • C15-H13-F-O2

Molecular Weight

  • 244.2637
 

Classification Code

  • Treatment of Alzheimer's Disease
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Names and Synonyms

Name of Substance

  • Tarenflurbil [USAN:INN]

Synonyms

  • (-)-(2R)-2-(2-Fluorobiphenyl-4-yl)propanoic acid
  • E-7869
  • EINECS 257-264-7
  • Flurizan
  • Furbiprofen
  • MPC-7869
  • R-Flurbiprofen
  • Tarenflurbil
  • UNII-501W00OOWA

Systematic Names

  • (1,1'-Biphenyl)-4-acetic acid, 2-fluoro-alpha-methyl-, (alphaR)-
  • (R)-2-Fluoro-alpha-methyl(1,1'-biphenyl)-4-acetic acid

Registry Numbers

CAS Registry Number

  • 51543-40-9

FDA UNII

  • 501W00OOWA

System Generated Number

  • 0051543409

Structure Descriptors

InChI

1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)/t10-/m1/s1

InChIKey

SYTBZMRGLBWNTM-SNVBAGLBSA-N

Smiles

c1(c(ccc(c1)[C@H](C(O)=O)C)c1ccccc1)F