Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Carteolol [INN:BAN]
RN: 51781-06-7
UNII: 8NF31401XG
InChIKey: LWAFSWPYPHEXKX-UHFFFAOYSA-N

Note

  • A beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.

Molecular Formula

  • C16-H24-N2-O3

Molecular Weight

  • 292.3766
 

Classification Codes

  • Adrenergic Agents
  • Adrenergic Antagonists
  • Adrenergic beta-Antagonists
  • Anti-Arrhythmia Agents
  • Antihypertensive Agents
  • Autonomic Agents
  • Cardiovascular Agents
  • Neurotransmitter Agents
  • Peripheral Nervous System Agents
  • Sympatholytics

Names and Synonyms

Name of Substance

  • Carteolol
  • Carteolol [INN:BAN]

MeSH Heading

  • Carteolol

Synonyms

  • Carteolol
  • Carteololum
  • Carteololum [INN-Latin]
  • UNII-8NF31401XG

Systematic Name

  • 2(1H)-Quinolinone, 5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-

Registry Numbers

CAS Registry Number

  • 51781-06-7

FDA UNII

  • 8NF31401XG

Related Registry Number

  • 51781-21-6 (mono hydrochloride)

System Generated Number

  • 0051781067

Structure Descriptors

InChI

1S/C16H24N2O3/c1-16(2,3)17-9-11(19)10-21-14-6-4-5-13-12(14)7-8-15(20)18-13/h4-6,11,17,19H,7-10H2,1-3H3,(H,18,20)

InChIKey

LWAFSWPYPHEXKX-UHFFFAOYSA-N

Smiles

CC(C)(C)NCC(O)COc1cccc2NC(=O)CCc12

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral 830mg/kg (830mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 323, 1980.
mouse LD50 oral 810mg/kg (810mg/kg)   Japanese Journal of Toxicology. Vol. 4, Pg. 121, 1991.
rabbit LD50 intravenous 112mg/kg (112mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 323, 1980.
rabbit LD50 oral 740mg/kg (740mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 323, 1980.

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) 1.420 (none)   EST
Atmospheric OH Rate Constant 2.63E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.