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Substance Name: Medroxyprogesterone [INN:BAN]
RN: 520-85-4
UNII: HSU1C9YRES
InChIKey: FRQMUZJSZHZSGN-HBNHAYAOSA-N

Note

  • (6 alpha)-17-Hydroxy-6-methylpregn-4-ene-3,20-dione. A synthetic progestational hormone used in veterinary practice as an estrus regulator.

Molecular Formula

  • C22-H32-O3

Molecular Weight

  • 344.4918
 

Classification Codes

  • Contraceptive Agents
  • Contraceptive Agents, Female
  • Contraceptives, Oral
  • Contraceptives, Oral, Synthetic
  • Hormone
  • Human Data
  • Reproductive Control Agents
  • Reproductive Effect

Names and Synonyms

Name of Substance

  • Medroxyprogesterone
  • Medroxyprogesterone [INN:BAN]

MeSH Heading

  • Medroxyprogesterone

Synonyms

  • 17-Hydroxy-6alpha-methyl-pregn-4-ene-3,20-dione
  • 17-Hydroxy-6alpha-methylprogesterone
  • 17alpha-Hydroxy-6alpha-methylprogesterone
  • 4-08-00-02211 (Beilstein Handbook Reference)
  • 6-alpha-Methyl-17-alpha-hydroxyprogesterone
  • 6alpha-Methyl-17alpha-hydroxyprogesterone
  • 6alpha-Methyl-4-pregnen-17alpha-ol-3,20-dione
  • Amen
  • BRN 2510965
  • Curretab
  • EINECS 208-298-6
  • HSDB 3114
  • Medrossiprogesterone
  • Medrossiprogesterone [DCIT]
  • Medroxiprogesterona
  • Medroxiprogesterona [INN-Spanish]
  • Medroxiprogesteronum
  • Medroxyprogesteron
  • Medroxyprogesterone
  • Medroxyprogesteronum
  • Medroxyprogesteronum [INN-Latin]
  • NSC 27408
  • U 8840
  • UNII-HSU1C9YRES

Systematic Names

  • Medroxyprogesterone
  • Pregn-4-ene-3,20-dione, 17-hydroxy-6-alpha-methyl-
  • Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6-alpha)- (9CI)
  • Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6alpha)-
  • Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6alpha)- (9CI)

Registry Numbers

CAS Registry Number

  • 520-85-4

FDA UNII

  • HSU1C9YRES

System Generated Number

  • 0000520854

Structure Descriptors

InChI

1S/C22H32O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h12-13,16-18,25H,5-11H2,1-4H3/t13-,16+,17-,18-,20+,21-,22-/m0/s1

InChIKey

FRQMUZJSZHZSGN-HBNHAYAOSA-N

Smiles

C[C@H]1C[C@@H]2[C@H](CC[C@]3([C@H]2CC[C@@]3(C(=O)C)O)C)[C@@]4(C1=CC(=O)CC4)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
women TDLo parenteral 6mg/kg/13W-I (6mg/kg) PERIPHERAL NERVE AND SENSATION: SENSORY CHANGE INVOLVING PERIPHERAL NERVE

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"
Medical Journal of Australia. Vol. 163, Pg. 51, 1995.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 214.5 deg C   EXP
log P (octanol-water) 3.500 (none)   EST
Atmospheric OH Rate Constant 1.04E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.