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Substance Name: Norcoralydine
RN: 523-02-4
InChIKey: YOAUKNYXWBTMMF-UHFFFAOYSA-N

Note

  • Neuromuscular blocking agent.

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C21-H25-N-O4

Molecular Weight

  • 355.431
 
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Names and Synonyms

Name of Substance

  • Norcoralydine

Synonyms

  • (-)-Xylopinine
  • 13a-alpha-Berbine, 2,3,10,11-tetramethoxy-
  • Govanine methyl ether
  • l-Xylopinine
  • Norcoralydine
  • NSC 17067
  • NSC 23898
  • O,O-Dimethylgovadine
  • O-Methylgovanine
  • S-(-)-Xylopinine

Systematic Names

  • 13aalpha-Berbine, 2,3,10,11-tetramethoxy- (8CI)
  • 6H-Dibenzo(a,g)quinolizine, 5,8,13,13a-tetrahydro-2,3,10,11-tetramethoxy-, (S)-

Registry Numbers

CAS Registry Number

  • 523-02-4

System Generated Number

  • 0000523024

Structure Descriptors

InChI

1S/C21H25NO4/c1-23-18-8-13-5-6-22-12-15-10-20(25-3)19(24-2)9-14(15)7-17(22)16(13)11-21(18)26-4/h8-11,17H,5-7,12H2,1-4H3

InChIKey

YOAUKNYXWBTMMF-UHFFFAOYSA-N

Smiles

c12[C@@H]3[N@@](Cc4cc(OC)c(cc4C3)OC)CCc1cc(OC)c(c2)OC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 62mg/kg (62mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: IRRITABILITY
Japanese Journal of Pharmacology. Vol. 16, Pg. 10, 1966.