Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Surfagon
RN: 52435-06-0
InChIKey: QLGKMLRGKPKGKI-MUVLZESKSA-N

Note

  • Potent LHRH agonist.

Classification Codes

  • Hormone
  • Human Data
  • Reproductive Effect

Molecular Formula

  • C56-H78-N16-O12

Molecular Weight

  • 1167.33
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Surfagon

Synonyms

  • (D-Ala(sup 6)-des-gly-NH2(sup 10))-luteinizing hormone-releasing hormone ethylamide
  • (D-Ala(sup 6)-des-gly-NH2(sup 10))LHRH ethylamide
  • 6-D-Alanine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-luteinizing hormone-releasing hormone
  • AY-25,205
  • BRN 0906592
  • Dalarelin
  • Dalareline
  • LHRH-A2
  • TAP 127
  • WY 18481

Systematic Name

  • Luteinizing hormone-releasing factor (pig), 6-D-alanine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-

Registry Numbers

CAS Registry Number

  • 52435-06-0

Other Registry Numbers

  • 53818-13-6
  • 56136-33-5
  • 67910-55-8

System Generated Number

  • 0052435060

Structure Descriptors

InChI

1S/C56H78N16O12/c1-5-60-54(83)45-13-9-21-72(45)55(84)39(12-8-20-61-56(57)58)66-50(79)40(22-30(2)3)67-47(76)31(4)64-49(78)41(23-32-14-16-35(74)17-15-32)68-53(82)44(28-73)71-51(80)42(24-33-26-62-37-11-7-6-10-36(33)37)69-52(81)43(25-34-27-59-29-63-34)70-48(77)38-18-19-46(75)65-38/h6-7,10-11,14-17,26-27,29-31,38-45,62,73-74H,5,8-9,12-13,18-25,28H2,1-4H3,(H,59,63)(H,60,83)(H,64,78)(H,65,75)(H,66,79)(H,67,76)(H,68,82)(H,69,81)(H,70,77)(H,71,80)(H4,57,58,61)/t31-,38?,39+,40+,41+,42+,43+,44?,45+/m1/s1

InChIKey

QLGKMLRGKPKGKI-MUVLZESKSA-N

Smiles

c1cc2c(c(C[C@H](NC(=O)[C@H](Cc3[nH]cnc3)NC(=O)[C@@H]3NC(CC3)=O)C(=O)N[C@@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N3CCC[C@H]3C(=O)NCC)=O)CCCNC(N)=N)=O)CC(C)C)=O)C)=O)Cc3ccc(cc3)O)=O)CO)c[nH]2)cc1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LDLo intravenous 50mg/kg (50mg/kg) BEHAVIORAL: ATAXIA Acta Europaea Fertilitatis. Vol. 11, Pg. 113, 1980.