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Substance Name: Glucametacin [INN]
RN: 52443-21-7
UNII: N1EXE5EHAN
InChIKey: XLVXAUNDHWERBM-IVGWJTKZSA-N

Note

  • Indomethacin analog.

Molecular Formulas

  • C25-H27-Cl-N2-O8
  • C25-H27-Cl-N2-O8.H2-O

Molecular Weight

  • 518.9473
 

Classification Codes

  • Analgesics
  • Analgesics, Non-Narcotic
  • Anti-Inflammatory Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Antirheumatic Agents
  • Drug / Therapeutic Agent
  • Human Data
  • Peripheral Nervous System Agents
  • Sensory System Agents
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Names and Synonyms

Name of Substance

  • Glucametacin
  • Glucametacin [INN]

Synonyms

  • 1-(p-Chlorbenzoyl)-5-methoxy-2-methylindol-3-essigsaeure-monohydrat-glucosamid
  • 1-(p-Chlorbenzoyl)-5-methoxy-2-methylindol-3-essigsaeure-monohydrat-glucosamid [German]
  • 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid monohydrate glucosamide
  • 2-(2-(1-(p-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl)acetamido)-2-deoxy-D-glucose
  • EINECS 257-923-9
  • Glucametacin
  • Glucametacina
  • Glucametacina [INN-Spanish]
  • Glucametacine
  • Glucametacine [INN-French]
  • Glucametacinum
  • Glucametacinum [INN-Latin]
  • Glucometacin
  • Teoremac
  • UNII-N1EXE5EHAN

Systematic Names

  • 2-(2-(1-(p-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl)acetamido)-2-deoxy-D-glucose
  • D-Glucose, 2-(((1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetyl)amino)-2-deoxy-
  • D-Glucose, 2-(((1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetyl)amino)-2-deoxy-, hydrate
  • Glucametacin

Registry Numbers

CAS Registry Number

  • 52443-21-7

FDA UNII

  • N1EXE5EHAN

System Generated Number

  • 0052443217

Molecular Formulas

Molecular Formulas

  • C25-H27-Cl-N2-O8
  • C25-H27-Cl-N2-O8.H2-O

Molecular Formula Fragments

  • C25-H27-Cl-N2-O8
  • COMPONENT
  • H2-O

Structure Descriptors

InChI

1S/C25H27ClN2O8/c1-13-17(10-22(32)27-19(11-29)23(33)24(34)21(31)12-30)18-9-16(36-2)7-8-20(18)28(13)25(35)14-3-5-15(26)6-4-14/h3-9,11,19,21,23-24,30-31,33-34H,10,12H2,1-2H3,(H,27,32)/t19-,21+,23+,24+/m0/s1

InChIKey

XLVXAUNDHWERBM-IVGWJTKZSA-N

Smiles

Cc1c(c2cc(ccc2n1C(=O)c3ccc(cc3)Cl)OC)CC(=O)N[C@@H](C=O)[C@H]([C@@H]([C@@H](CO)O)O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human TDLo oral 84mg/kg/14D-I (84mg/kg) GASTROINTESTINAL: OTHER CHANGES

BEHAVIORAL: HEADACHE
Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 435, 1975.

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) 2.250 (none)   EST
Atmospheric OH Rate Constant 3.14E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.