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Substance Name: Estrone [USP:INN:BAN]
RN: 53-16-7
UNII: 2DI9HA706A
InChIKey: DNXHEGUUPJUMQT-CBZIJGRNSA-N
Note
- An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.
Molecular Formula
- C18-H22-O2
Molecular Weight
- 270.3698
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Physical Properties
Classification Codes
Classification Codes
- Antiviral (COVID-19)
- Drug / Therapeutic Agent
- Estrogen
- Estrogens
- Hormone
- Hormones
- Hormones, Hormone Substitutes, and Hormone Antagonists
- Human Data
- Mutation Data
- Natural Product
- Reproductive Effect
- Tumor Data
Superlist Classification Code
- Reasonably Anticipated to be a Carcinogen
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Links to Resources
NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
Search for this InChIKey on the Web
Names and Synonyms
Name of Substance
- Estrone
- Estrone [USP:INN:BAN]
MeSH Heading
- Estrone
Synonyms
- 1,3,5(10)-Estratrien-3-ol-17-one
- 1,3,5(10)-Oestratrien-3-ol-17-one
- 3-08-00-01171 (Beilstein Handbook Reference)
- 3-Hydroxy-17-keto-estra-1,3,5-triene
- 3-Hydroxy-17-keto-oestra-1,3,5-triene
- 3-Hydroxy-oestra-1,3,5(10)-trien-17-one
- 3-Hydroxyestra-1,3,5(10)-trien-17-one
- 3-Hydroxyestra-1,3,5(10)-triene-17-one
- Aquacrine
- BRN 1915077
- CCRIS 285
- Crinovaryl
- Cristallovar
- Crystogen
- delta-1,3,5-estratrien-3-beta-ol-17-one
- delta-1,3,5-Estratrien-3beta-ol-17-one
- delta-1,3,5-oestratrien-3-beta-ol-17-one
- delta-1,3,5-Oestratrien-3beta-ol-17-one
- Destrone
- Disynformon
- E(sub 1)
- EC 200-164-5
- EINECS 200-164-5
- Endofolliculina
- Estra-1,3,5(10)-trien-17-one, 3-hydroxy-
- Estrogenic substance
- Estron
- Estrona
- Estrona [INN-Spanish]
- Estrona [Spanish]
- Estrone
- Estrone-A
- Estronum
- Estronum [INN-Latin]
- Estrovarin
- Estrugenone
- Estrusol
- Fem-O-Gen
- Femestrone injection
- Femidyn
- Folikrin
- Folipex
- Folisan
- Follestrine
- Follestrol
- Follicular hormone
- Folliculin
- Folliculine
- Folliculine benzoate
- Follicunodis
- Glandubolin
- Hiestrone
- Hormestrin
- Hormofollin
- Hormovarine
- HSDB 3324
- Kestrone
- Ketodestrin
- Ketohydroxy-estratriene
- Ketohydroxyestrin
- Ketohydroxyoestrin
- Kolpon
- Menagen
- Menformon
- Mestronaq
- Natural estrogenic substance-estrone
- NSC 9699
- Oestrin
- Oestroform
- Oestrone
- Oestronum
- Oestroperos
- Ovex (tablets)
- Ovifollin
- Perlatan
- Solliculin
- Theelin
- Thelestrin
- Thelykinin
- Thynestron
- Tokokin
- Unden
- Unden (pharmaceutical)
- Unden (pharmaceutical) (VAN)
- UNII-2DI9HA706A
- Wynestron
Systematic Names
- Estra-1,3,5(10)-trien-17-one, 3-hydroxy-
- Estrone
Superlist Names
- Estra-1,3,5(10)-trien-17-one, 3-hydroxy-
- Estrone
- Oestrone
- Oestrone [Steroidal oestrogens]
Registry Numbers
CAS Registry Number
- 53-16-7
FDA UNII
- 2DI9HA706A
Other Registry Number
- 37242-41-4
System Generated Number
- 0000053167
Structure Descriptors
InChI
InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1InChIKey
DNXHEGUUPJUMQT-CBZIJGRNSA-NSmiles
C[C@]12CC[C@H]3[C@@H](CCc4cc(O)Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 260.2 | deg C | EXP | |
Boiling Point | 154 | deg C | EXP | |
log P (octanol-water) | 3.13 | (none) | EXP | |
Water Solubility | 30 | mg/L | 25 | EXP |
Vapor Pressure | 1.42E-07 | mm Hg | 25 | EST |
Henry's Law Constant | 3.80E-10 | atm-m3/mole | 25 | EST |
Atmospheric OH Rate Constant | 1.26E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.