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Substance Name: Estrone [USP:INN:BAN]
RN: 53-16-7
UNII: 2DI9HA706A
InChIKey: DNXHEGUUPJUMQT-CBZIJGRNSA-N

Note

  • An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.

Molecular Formula

  • C18-H22-O2

Molecular Weight

  • 270.3698
 

Classification Codes

Classification Codes

  • Antiviral (COVID-19)
  • Drug / Therapeutic Agent
  • Estrogen
  • Estrogens
  • Hormone
  • Hormones
  • Hormones, Hormone Substitutes, and Hormone Antagonists
  • Human Data
  • Mutation Data
  • Natural Product
  • Reproductive Effect
  • Tumor Data

Superlist Classification Code

  • Reasonably Anticipated to be a Carcinogen
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Names and Synonyms

Name of Substance

  • Estrone
  • Estrone [USP:INN:BAN]

MeSH Heading

  • Estrone

Synonyms

  • 1,3,5(10)-Estratrien-3-ol-17-one
  • 1,3,5(10)-Oestratrien-3-ol-17-one
  • 3-08-00-01171 (Beilstein Handbook Reference)
  • 3-Hydroxy-17-keto-estra-1,3,5-triene
  • 3-Hydroxy-17-keto-oestra-1,3,5-triene
  • 3-Hydroxy-oestra-1,3,5(10)-trien-17-one
  • 3-Hydroxyestra-1,3,5(10)-trien-17-one
  • 3-Hydroxyestra-1,3,5(10)-triene-17-one
  • Aquacrine
  • BRN 1915077
  • CCRIS 285
  • Crinovaryl
  • Cristallovar
  • Crystogen
  • delta-1,3,5-estratrien-3-beta-ol-17-one
  • delta-1,3,5-Estratrien-3beta-ol-17-one
  • delta-1,3,5-oestratrien-3-beta-ol-17-one
  • delta-1,3,5-Oestratrien-3beta-ol-17-one
  • Destrone
  • Disynformon
  • E(sub 1)
  • EC 200-164-5
  • EINECS 200-164-5
  • Endofolliculina
  • Estra-1,3,5(10)-trien-17-one, 3-hydroxy-
  • Estrogenic substance
  • Estron
  • Estrona
  • Estrona [INN-Spanish]
  • Estrona [Spanish]
  • Estrone
  • Estrone-A
  • Estronum
  • Estronum [INN-Latin]
  • Estrovarin
  • Estrugenone
  • Estrusol
  • Fem-O-Gen
  • Femestrone injection
  • Femidyn
  • Folikrin
  • Folipex
  • Folisan
  • Follestrine
  • Follestrol
  • Follicular hormone
  • Folliculin
  • Folliculine
  • Folliculine benzoate
  • Follicunodis
  • Glandubolin
  • Hiestrone
  • Hormestrin
  • Hormofollin
  • Hormovarine
  • HSDB 3324
  • Kestrone
  • Ketodestrin
  • Ketohydroxy-estratriene
  • Ketohydroxyestrin
  • Ketohydroxyoestrin
  • Kolpon
  • Menagen
  • Menformon
  • Mestronaq
  • Natural estrogenic substance-estrone
  • NSC 9699
  • Oestrin
  • Oestroform
  • Oestrone
  • Oestronum
  • Oestroperos
  • Ovex (tablets)
  • Ovifollin
  • Perlatan
  • Solliculin
  • Theelin
  • Thelestrin
  • Thelykinin
  • Thynestron
  • Tokokin
  • Unden
  • Unden (pharmaceutical)
  • Unden (pharmaceutical) (VAN)
  • UNII-2DI9HA706A
  • Wynestron

Systematic Names

  • Estra-1,3,5(10)-trien-17-one, 3-hydroxy-
  • Estrone

Superlist Names

  • Estra-1,3,5(10)-trien-17-one, 3-hydroxy-
  • Estrone
  • Oestrone
  • Oestrone [Steroidal oestrogens]

Registry Numbers

CAS Registry Number

  • 53-16-7

FDA UNII

  • 2DI9HA706A

Other Registry Number

  • 37242-41-4

System Generated Number

  • 0000053167

Structure Descriptors

InChI

InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1

InChIKey

DNXHEGUUPJUMQT-CBZIJGRNSA-N

Smiles

C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CCC2=O

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 260.2 deg C   EXP
Boiling Point 154 deg C   EXP
log P (octanol-water) 3.13 (none)   EXP
Water Solubility 30 mg/L 25 EXP
Vapor Pressure 1.42E-07 mm Hg 25 EST
Henry's Law Constant 3.80E-10 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.26E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.