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Substance Name: Ribostamycin sulfate [JAN]
RN: 53797-35-6
UNII: QFN1QU7PEN
InChIKey: RTCDDYYZMGGHOE-YMSVYGIHSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C17-H34-N4-O10.x-H2-O4-S

Molecular Weight

  • 552.5514
 
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Names and Synonyms

Name of Substance

  • Ribostamycin sulfate
  • Ribostamycin sulfate [JAN]

Synonyms

  • EINECS 258-783-1
  • Landamycine
  • Riboflavine sulfate
  • Ribomycine
  • Ribostamin
  • Ribostamycin sulfate
  • SF 733 antibioic sulfate
  • UNII-QFN1QU7PEN

Systematic Names

  • Ribostamycin sulphate
  • Streptamine, O-2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-4)-O-(beta-D-ribofuranosyl-(1-5))-2-deoxy-, sulfate

Registry Numbers

CAS Registry Number

  • 53797-35-6

FDA UNII

  • QFN1QU7PEN

System Generated Number

  • 0053797356

Molecular Formulas

Molecular Formula

  • C17-H34-N4-O10.x-H2-O4-S

Molecular Formula Fragments

  • C17-H34-N4-O10
  • COMPONENT
  • H2-O4-S

Structure Descriptors

InChI

1S/C17H34N4O10.H2O4S/c18-2-6-10(24)12(26)8(21)16(28-6)30-14-5(20)1-4(19)9(23)15(14)31-17-13(27)11(25)7(3-22)29-17;1-5(2,3)4/h4-17,22-27H,1-3,18-21H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8-,9+,10-,11-,12-,13-,14-,15-,16-,17+;/m1./s1

InChIKey

RTCDDYYZMGGHOE-YMSVYGIHSA-N

Smiles

NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)[C@H](N)[C@@H](O)[C@@H]1O.OS(=O)(=O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intramuscular 1561mg/kg (1561mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 90, 1973.
mouse LD50 intraperitoneal 1981mg/kg (1981mg/kg)   Japan Medical Gazette. Vol. 10(2), Pg. 5, 1973.
mouse LD50 intravenous 210mg/kg (210mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 90, 1973.
mouse LD50 oral > 7gm/kg (7000mg/kg)   Drugs in Japan Vol. 6, Pg. 885, 1982.
mouse LD50 subcutaneous 2345mg/kg (2345mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 90, 1973.
rat LD50 intramuscular 2030mg/kg (2030mg/kg)   Drugs in Japan Vol. 6, Pg. 885, 1982.
rat LD50 intraperitoneal 3080mg/kg (3080mg/kg)   Japan Medical Gazette. Vol. 10(2), Pg. 5, 1973.
rat LD50 intravenous 375mg/kg (375mg/kg)   Japan Medical Gazette. Vol. 10(2), Pg. 5, 1973.
rat LD50 oral > 7gm/kg (7000mg/kg)   Drugs in Japan Vol. 6, Pg. 885, 1982.
rat LD50 subcutaneous 5600mg/kg (5600mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 90, 1973.