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Substance Name: Corticotropin-like intermediate lobe peptide
RN: 53917-42-3
InChIKey: ZYDMZKPAPSZILB-XDGGXQJNSA-N

Note

  • A peptide derived from the cleavage of ADRENOCORTICOTROPIC HORMONE, found primarily in the INTERMEDIATE LOBE OF PITUITARY but also in the ARCUATE NUCLEUS of basal HYPOTHALAMUS. Its sequence is identical to the C-terminal 22-amino acids of ACTH or ACTH 18-39.

Molecular Formula

  • C112-H165-N27-O36

Molecular Weight

  • 2465.69
 
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Names and Synonyms

Name of Substance

  • Corticotropin-like intermediate lobe peptide

MeSH Heading

  • Corticotropin-like intermediate lobe peptide

Synonyms

  • 31-Ser-acthalpha(18-39)
  • Acth(18-39)
  • Acthalpha(18-39), ser(31)-
  • Acthalpha(18-39), serine(31)-
  • CLILP

Systematic Name

  • Corticotropin-like intermediate lobe peptide (human)

Registry Numbers

CAS Registry Number

  • 53917-42-3

System Generated Number

  • 0053917423

Structure Descriptors

InChI

1S/C112H165N27O36/c1-56(2)48-72(100(163)125-70(37-41-86(148)149)97(160)133-77(111(174)175)51-63-24-14-11-15-25-63)129-103(166)79-28-20-46-138(79)109(172)75(49-62-22-12-10-13-23-62)131-93(156)61(9)121-95(158)68(35-39-84(144)145)123-92(155)60(8)122-102(165)78(55-140)134-98(161)71(38-42-87(150)151)126-101(164)74(53-88(152)153)128-96(159)69(36-40-85(146)147)124-91(154)59(7)120-83(143)54-119-94(157)73(52-82(115)142)130-104(167)80-29-21-47-139(80)110(173)76(50-64-31-33-65(141)34-32-64)132-107(170)89(57(3)4)135-99(162)67(27-16-17-43-113)127-106(169)90(58(5)6)136-105(168)81-30-19-45-137(81)108(171)66(114)26-18-44-118-112(116)117/h10-15,22-25,31-34,56-61,66-81,89-90,140-141H,16-21,26-30,35-55,113-114H2,1-9H3,(H2,115,142)(H,119,157)(H,120,143)(H,121,158)(H,122,165)(H,123,155)(H,124,154)(H,125,163)(H,126,164)(H,127,169)(H,128,159)(H,129,166)(H,130,167)(H,131,156)(H,132,170)(H,133,160)(H,134,161)(H,135,162)(H,136,168)(H,144,145)(H,146,147)(H,148,149)(H,150,151)(H,152,153)(H,174,175)(H4,116,117,118)/t59-,60-,61-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81?,89-,90-/m0/s1

InChIKey

ZYDMZKPAPSZILB-XDGGXQJNSA-N

Smiles

N1([C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@@H](CC(C)C)C(=O)N[C@H](C(N[C@@H](Cc3ccccc3)C(O)=O)=O)CCC(=O)O)=O)CCC2)=O)Cc2ccccc2)=O)C)=O)CCC(=O)O)=O)CCC(=O)O)=O)CC(O)=O)=O)CCC(O)=O)=O)C)=O)=O)CC(=O)N)=O)CCC1)C([C@@H](NC(=O)[C@@H](NC([C@@H](NC([C@@H](NC([C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)N)=O)C(C)C)=O)CCCCN)=O)C(C)C)Cc1ccc(cc1)O)=O