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Substance Name: Hygrolytin
RN: 53988-66-2

Note

  • Proteolytic enzyme produced by Actinomyces hygroscopicus.
 

Classification Code

  • Drug / Therapeutic Agent
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Names and Synonyms

  • Hygrolytin

Registry Numbers

CAS Registry Number

  • 53988-66-2

System Generated Number

  • 0053988662

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 100mg/kg (100mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION Pharmaceutical Chemistry Journal Vol. 11, Pg. 1052, 1977.
mouse LD50 intravenous 112mg/kg (112mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION Pharmaceutical Chemistry Journal Vol. 11, Pg. 1052, 1977.
mouse LD50 oral 2300mg/kg (2300mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION Pharmaceutical Chemistry Journal Vol. 11, Pg. 1052, 1977.
rabbit LD50 intravenous 44mg/kg (44mg/kg)   Pharmaceutical Chemistry Journal Vol. 11, Pg. 1052, 1977.
rabbit LD50 intravenous 44mg/kg (44mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION Pharmaceutical Chemistry Journal Vol. 11, Pg. 1052, 1977.
rat LD50 intraperitoneal 116mg/kg (116mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION Pharmaceutical Chemistry Journal Vol. 11, Pg. 1052, 1977.
rat LD50 intravenous 130mg/kg (130mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION Pharmaceutical Chemistry Journal Vol. 11, Pg. 1052, 1977.
rat LD50 oral 5gm/kg (5000mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION Pharmaceutical Chemistry Journal Vol. 11, Pg. 1052, 1977.