|
|
|
Substance Name: Moxisylyte [INN:BAN:DCF]
RN: 54-32-0
UNII: PW8QYA7KI0
InChIKey: VRYMTAVOXVTQEF-UHFFFAOYSA-N
Note
- An alpha-adrenergic blocking agent that is used in Raynaud's disease. It is also used locally in the eye to reverse the mydriasis caused by phenylephrine and other sympathomimetic agents. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1312)
Molecular Formula
- C16-H25-N-O3
Molecular Weight
- 279.378
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Adrenergic Agents
- Adrenergic alpha-Antagonists
- Adrenergic Antagonists
- Autonomic Agents
- Cardiovascular Agents
- Drug / Therapeutic Agent
- Miotics
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- Sympatholytics
- Vasodilator Agents
* denotes mobile formatted website
Links to Resources
NLM Resources (File Locators)
Other Resources (Internet Locators)
Search for this InChIKey on the Web
Names and Synonyms
Name of Substance
- Moxisylyte
- Moxisylyte [INN:BAN:DCF]
MeSH Heading
- Moxisylyte
Synonyms
- (2-(4-Acetoxy-2-isopropyl-5-methylphenoxy)ethyl)dimethylamine
- 4-(2-(Dimethylamino)ethoxy)-2-methyl-5-(1-methylethyl)phenol acetate (ester)
- Arlytene
- Carvacrol, 5-(2-(dimethylamino)ethoxy)-, acetate (ester)
- EINECS 200-204-1
- Moxilite
- Moxisilita
- Moxisilita [INN-Spanish]
- Moxisylyt
- Moxisylyte
- Moxisylytum
- Moxisylytum [INN-Latin]
- Sympal
- Thymoxamine
- Timoxamina
- UNII-PW8QYA7KI0
- Vasoklin
Systematic Names
- (2-(4-Acetoxy-2-isopropyl-5-methylphenoxy)ethyl)dimethylamine
- Moxisylyte
- Phenol, 4-(2-(dimethylamino)ethoxy)-2-methyl-5-(1-methylethyl)-, acetate (ester)
Registry Numbers
CAS Registry Number
- 54-32-0
FDA UNII
- PW8QYA7KI0
System Generated Number
- 0000054320
Structure Descriptors
InChI
1S/C16H25NO3/c1-11(2)14-10-15(20-13(4)18)12(3)9-16(14)19-8-7-17(5)6/h9-11H,7-8H2,1-6H3InChIKey
VRYMTAVOXVTQEF-UHFFFAOYSA-NSmiles
c1(c(cc(C)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 73mg/kg (73mg/kg) | European Patent Application. Vol. #0062596, | |
| mouse | LD50 | oral | 225mg/kg (225mg/kg) | European Patent Application. Vol. #0062596, |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Melting Point | 144.5 | deg C | EXP | |
| pKa Dissociation Constant | 8.72 | (none) | EXP | |
| log P (octanol-water) | 3.17 | (none) | EXP | |
| Water Solubility | 323 | mg/L | 25 | EST |
| Vapor Pressure | 2.78E-05 | mm Hg | 25 | EST |
| Henry's Law Constant | 5.42E-09 | atm-m3/mole | 25 | EST |
| Atmospheric OH Rate Constant | 1.58E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.