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Substance Name: Pyridoxal phosphate
RN: 54-47-7
UNII: F06SGE49M6
InChIKey: NGVDGCNFYWLIFO-UHFFFAOYSA-N
Note
- This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
Molecular Formula
- C8-H10-N-O6-P
Molecular Weight
- 247.142
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- Drug / Therapeutic Agent
- Growth Substances
- Micronutrients
- Mutation Data
- Vitamin B Complex
- Vitamins
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Names and Synonyms
Results Name
- Pyridoxal phosphate
Name of Substance
- 3-Hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyde
- 4-Pyridinecarboxaldehyde, 3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-
- Pyridoxal 5-phosphate
- Pyridoxal calcium phosphate [JAN]
- Pyridoxal phosphate
MeSH Heading
- Pyridoxal phosphate
Synonyms
- 2-Methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine-5-calcium phosphate trihydrate
- 4-Pyridinecarboxaldehyde, 3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-
- Apolon B(sub 6)
- Apolon B6
- Biosechs
- Codecarboxylase
- Coenzyme B6
- EINECS 200-208-3
- Hairoxal
- Hexermin P
- HI-Pyridoxin
- Hiadelon
- Himitan
- NSC 82388
- Pal-P
- Phosphopyridoxal
- Phosphopyridoxal coenzyme
- Phosphoridoxal coenzyme
- Pidopidon
- Piodel
- PLP
- Pydoxal
- Pyridoxal 5-phosphate
- Pyridoxal calcium phosphate
- Pyridoxal monophosphate
- Pyridoxal P
- Pyridoxal phosphate
- Pyridoxal-5'-phosphate
- Pyridoxaldehyde phosphate
- Pyridoxyl phosphate
- Pyromijin
- Sechvitan
- UNII-F06SGE49M6
- Vitahexin P
- Vitazechs
Systematic Names
- 2-Methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine-5-calcium phosphate
- 4-Pyridinecarboxaldehyde, 3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-
- Pyridoxal 5'-(dihydrogen phosphate)
Registry Numbers
CAS Registry Number
- 54-47-7
FDA UNII
- F06SGE49M6
Other Registry Numbers
- 1071665-72-9
- 52064-48-9
- 52441-27-7
System Generated Number
- 0000054477
Structure Descriptors
InChI
InChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)InChIKey
NGVDGCNFYWLIFO-UHFFFAOYSA-NSmiles
Cc1ncc(COP(=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mammal (species unspecified) | LD50 | oral | > 3gm/kg (3000mg/kg) | British Patent Document. Vol. #1172800, | |
mammal (species unspecified) | LD50 | subcutaneous | 550mg/kg (550mg/kg) | British Patent Document. Vol. #1172800, | |
mouse | LD50 | intramuscular | 1150mg/kg (1150mg/kg) | BEHAVIORAL: ANTIPSYCHOTIC | Pharmaceutical Chemistry Journal Vol. 15, Pg. 303, 1981. |
mouse | LD50 | intravenous | 530mg/kg (530mg/kg) | Drugs in Japan Vol. 6, Pg. 643, 1982. | |
mouse | LD50 | oral | 4640mg/kg (4640mg/kg) | Drugs in Japan Vol. 6, Pg. 643, 1982. | |
mouse | LD50 | subcutaneous | 870mg/kg (870mg/kg) | Drugs in Japan Vol. 6, Pg. 643, 1982. | |
rat | LD50 | oral | 5900mg/kg (5900mg/kg) | Drugs in Japan Vol. 6, Pg. 643, 1982. | |
rat | LD50 | subcutaneous | 850mg/kg (850mg/kg) | Drugs in Japan Vol. 6, Pg. 643, 1982. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 255 | deg C | EXP | |
log P (octanol-water) | 0.370 | (none) | EST | |
Water Solubility | 1.19E+04 | mg/L | 25 | EST |
Vapor Pressure | 3.28E-10 | mm Hg | 25 | EST |
Henry's Law Constant | 9.26E-20 | atm-m3/mole | 25 | EST |
Atmospheric OH Rate Constant | 4.29E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.