Skip Navigation
ChemIDplus Lite•Browse•Advanced

Substance Name: Pyridoxal phosphate
RN: 54-47-7
UNII: F06SGE49M6
InChIKey: NGVDGCNFYWLIFO-UHFFFAOYSA-N

Note

  • This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).

Molecular Formula

  • C8-H10-N-O6-P

Molecular Weight

  • 247.142
 

Classification Codes

  • Drug / Therapeutic Agent
  • Growth Substances
  • Micronutrients
  • Mutation Data
  • Vitamin B Complex
  • Vitamins
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Regulatory Agencies (Superlist Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Results Name

  • Pyridoxal phosphate

Name of Substance

  • 3-Hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyde
  • 4-Pyridinecarboxaldehyde, 3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-
  • Pyridoxal 5-phosphate
  • Pyridoxal calcium phosphate [JAN]
  • Pyridoxal phosphate

MeSH Heading

  • Pyridoxal phosphate

Synonyms

  • 2-Methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine-5-calcium phosphate trihydrate
  • 4-Pyridinecarboxaldehyde, 3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-
  • Apolon B(sub 6)
  • Apolon B6
  • Biosechs
  • Codecarboxylase
  • Coenzyme B6
  • EINECS 200-208-3
  • Hairoxal
  • Hexermin P
  • HI-Pyridoxin
  • Hiadelon
  • Himitan
  • NSC 82388
  • Pal-P
  • Phosphopyridoxal
  • Phosphopyridoxal coenzyme
  • Phosphoridoxal coenzyme
  • Pidopidon
  • Piodel
  • PLP
  • Pydoxal
  • Pyridoxal 5-phosphate
  • Pyridoxal calcium phosphate
  • Pyridoxal monophosphate
  • Pyridoxal P
  • Pyridoxal phosphate
  • Pyridoxal-5'-phosphate
  • Pyridoxaldehyde phosphate
  • Pyridoxyl phosphate
  • Pyromijin
  • Sechvitan
  • UNII-F06SGE49M6
  • Vitahexin P
  • Vitazechs

Systematic Names

  • 2-Methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine-5-calcium phosphate
  • 4-Pyridinecarboxaldehyde, 3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-
  • Pyridoxal 5'-(dihydrogen phosphate)

Registry Numbers

CAS Registry Number

  • 54-47-7

FDA UNII

  • F06SGE49M6

Other Registry Numbers

  • 1071665-72-9
  • 52064-48-9
  • 52441-27-7

System Generated Number

  • 0000054477

Structure Descriptors

InChI

InChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)

InChIKey

NGVDGCNFYWLIFO-UHFFFAOYSA-N

Smiles

Cc1ncc(COP(=O)(O)O)c(C=O)c1O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mammal (species unspecified) LD50 oral > 3gm/kg (3000mg/kg)   British Patent Document. Vol. #1172800,
mammal (species unspecified) LD50 subcutaneous 550mg/kg (550mg/kg)   British Patent Document. Vol. #1172800,
mouse LD50 intramuscular 1150mg/kg (1150mg/kg) BEHAVIORAL: ANTIPSYCHOTIC Pharmaceutical Chemistry Journal Vol. 15, Pg. 303, 1981.
mouse LD50 intravenous 530mg/kg (530mg/kg)   Drugs in Japan Vol. 6, Pg. 643, 1982.
mouse LD50 oral 4640mg/kg (4640mg/kg)   Drugs in Japan Vol. 6, Pg. 643, 1982.
mouse LD50 subcutaneous 870mg/kg (870mg/kg)   Drugs in Japan Vol. 6, Pg. 643, 1982.
rat LD50 oral 5900mg/kg (5900mg/kg)   Drugs in Japan Vol. 6, Pg. 643, 1982.
rat LD50 subcutaneous 850mg/kg (850mg/kg)   Drugs in Japan Vol. 6, Pg. 643, 1982.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 255 deg C   EXP
log P (octanol-water) 0.370 (none)   EST
Water Solubility 1.19E+04 mg/L 25 EST
Vapor Pressure 3.28E-10 mm Hg 25 EST
Henry's Law Constant 9.26E-20 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 4.29E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.