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Substance Name: Nitrofurantoin sodium
RN: 54-87-5
UNII: MAL9M0T5LV
InChIKey: AFDJQFFKYDCYIG-JSGFVSQVSA-M
Note
- A urinary anti-infective agent effective against most gram-positive and gram-negative organisms. Although sulfonamides and antibiotics are usually the agents of choice for urinary tract infections, nitrofurantoin is widely used for prophylaxis and long-term suppression.
Molecular Formula
- C8-H6-N4-O5.Na
Molecular Weight
- 260.1405
- All
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- Registry Numbers
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- Structure Descriptors
- Toxicity
Classification Codes
Classification Codes
- Drug / Therapeutic Agent
- Tumor Data
Superlist Classification Code
- Overall Carcinogenic Evaluation: Group 3
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Names and Synonyms
Name of Substance
- Nitrofurantoin sodium
Synonyms
- EINECS 200-216-7
- Ivadantin
- Nitrofurandantoin sodium
- Nitrofurantoin sodium
- Sodium furadantin
- Sodium nitrofurantoin
- UNII-MAL9M0T5LV
Systematic Names
- 1-((5-Nitrofurfurylidene)amino)imidazolidine-2,4-dione, sodium salt
- 2,4-Imidazolidinedione, 1-(((5-nitro-2-furanyl)methylene)amino)-, sodium salt
- Hydantoin, 1-((5-nitrofurfurylidene)amino)-, sodium salt
- Sodium, (3-((5-nitrofurfurylidene)amino)-2,5-dioxo-1-imidazolidinyl)-
Superlist Name
- Nitrofurantoin sodium
Registry Numbers
CAS Registry Number
- 54-87-5
FDA UNII
- MAL9M0T5LV
Related Registry Number
- 67-20-9 (Parent)
System Generated Number
- 0000054875
Molecular Formulas
Molecular Formula
- C8-H6-N4-O5.Na
Molecular Formula Fragments
- C8-H6-N4-O5
- COMPONENT
- Na
Structure Descriptors
InChI
InChI=1S/C8H6N4O5.Na/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16;/h1-3H,4H2,(H,10,13,14);/q;+1/p-1/b9-3+;InChIKey
AFDJQFFKYDCYIG-JSGFVSQVSA-MSmiles
[Na+].[O-][N+](=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
rat | LD50 | oral | 1493mg/kg (1493mg/kg) | Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971. | |
rat | LD50 | subcutaneous | 178mg/kg (178mg/kg) | Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971. |