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Substance Name: Nitrofurantoin sodium
RN: 54-87-5
UNII: MAL9M0T5LV
InChIKey: AFDJQFFKYDCYIG-JSGFVSQVSA-M

Note

  • A urinary anti-infective agent effective against most gram-positive and gram-negative organisms. Although sulfonamides and antibiotics are usually the agents of choice for urinary tract infections, nitrofurantoin is widely used for prophylaxis and long-term suppression.

Molecular Formula

  • C8-H6-N4-O5.Na

Molecular Weight

  • 260.1405
 

Classification Codes

Classification Codes

  • Drug / Therapeutic Agent
  • Tumor Data

Superlist Classification Code

  • Overall Carcinogenic Evaluation: Group 3
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Names and Synonyms

Name of Substance

  • Nitrofurantoin sodium

Synonyms

  • EINECS 200-216-7
  • Ivadantin
  • Nitrofurandantoin sodium
  • Nitrofurantoin sodium
  • Sodium furadantin
  • Sodium nitrofurantoin
  • UNII-MAL9M0T5LV

Systematic Names

  • 1-((5-Nitrofurfurylidene)amino)imidazolidine-2,4-dione, sodium salt
  • 2,4-Imidazolidinedione, 1-(((5-nitro-2-furanyl)methylene)amino)-, sodium salt
  • Hydantoin, 1-((5-nitrofurfurylidene)amino)-, sodium salt
  • Sodium, (3-((5-nitrofurfurylidene)amino)-2,5-dioxo-1-imidazolidinyl)-

Superlist Name

  • Nitrofurantoin sodium

Registry Numbers

CAS Registry Number

  • 54-87-5

FDA UNII

  • MAL9M0T5LV

Related Registry Number

  • 67-20-9 (Parent)

System Generated Number

  • 0000054875

Molecular Formulas

Molecular Formula

  • C8-H6-N4-O5.Na

Molecular Formula Fragments

  • C8-H6-N4-O5
  • COMPONENT
  • Na

Structure Descriptors

InChI

InChI=1S/C8H6N4O5.Na/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16;/h1-3H,4H2,(H,10,13,14);/q;+1/p-1/b9-3+;

InChIKey

AFDJQFFKYDCYIG-JSGFVSQVSA-M

Smiles

[Na+].[O-][N+](=O)c1oc(\C=N\N2CC(=O)[N-]C2=O)cc1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 oral 1493mg/kg (1493mg/kg)   Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.
rat LD50 subcutaneous 178mg/kg (178mg/kg)   Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.