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Substance Name: Levocarnitine [USAN:USP:INN:BAN]
RN: 541-15-1
UNII: 0G389FZZ9M
InChIKey: PHIQHXFUZVPYII-ZCFIWIBFSA-N

Note

  • Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.

Molecular Formula

  • C7-H15-N-O3

Molecular Weight

  • 161.1995
 

Classification Codes

  • Antihyperlipoproteinemic
  • Drug / Therapeutic Agent
  • Growth Substances
  • Micronutrients
  • Natural Product
  • Replenisher (Carnitine)
  • Vitamin B Complex
  • Vitamins

Names and Synonyms

Name of Substance

  • 1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, hydroxide, inner salt
  • 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner salt
  • L-Carnitine
  • Levocarnitine [USAN:USP:INN:BAN]

MeSH Heading

  • Carnitine

Synonyms

  • (-)-Carnitine
  • (-)-L-Carnitine
  • (3-Carboxy-2-hydroxypropyl)trimethyl-ammonium hydroxide, inner salt
  • (L-3-Carboxy-2-hydroxypropyl)trimethylammonium hydroxide, inner salt
  • (R)-Carnitine
  • 1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, hydroxide, inner salt, (R)-
  • 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner salt
  • Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, hydroxide, inner salt, L-
  • Carnitine
  • Carnitine, (-)-
  • Carnitolo
  • Carnitor
  • Carnitor SF
  • Carnovis
  • Carrier
  • EINECS 208-768-0
  • gamma-Trimethyl-ammonium-beta-hydroxybutirate
  • gamma-Trimethyl-beta-hydroxybutyrobetaine
  • HSDB 7588
  • Karnitin
  • L-(-)-Carnitine
  • L-Carnitine
  • Lefcar
  • Levocarnitina
  • Levocarnitina [Spanish]
  • Levocarnitine
  • Levocarnitinum
  • Levocarnitinum [Latin]
  • Metina
  • ST 198
  • UNII-0G389FZZ9M
  • Vitamin BT

Systematic Names

  • (R)-(3-Carboxy-2-hydroxypropyl)trimethylammonium hydroxide
  • 1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, hydroxide, inner salt, (R)-
  • 1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, inner salt, (R)-
  • Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, hydroxide, inner salt, L-

Superlist Name

  • Carnitine

Registry Numbers

CAS Registry Number

  • 541-15-1

FDA UNII

  • 0G389FZZ9M

Other Registry Number

  • 7634-98-2

System Generated Number

  • 0000541151

Structure Descriptors

InChI

1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1

InChIKey

PHIQHXFUZVPYII-ZCFIWIBFSA-N

Smiles

C[N+](C)(C)C[C@H](O)CC(=O)[O-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 unreported 7gm/kg (7000mg/kg)   Cancer Treatment Reports. Vol. 63, Pg. 558, 1979.
mouse LD50 intraperitoneal 750mg/kg (750mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 759, 1967.
mouse LD50 subcutaneous 9gm/kg (9000mg/kg) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Acta Biologica et Medica Germanica. Vol. 35, Pg. 645, 1976.