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Substance Name: Benzphetamine hydrochloride [NF]
RN: 5411-22-3
UNII: 43DWT87QT7
InChIKey: ANFSNXAXVLRZCG-RSAXXLAASA-N

Note

  • A sympathomimetic agent with properties similar to DEXTROAMPHETAMINE. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)

Molecular Formula

  • C17-H21-N.Cl-H

Molecular Weight

  • 275.8208
 

Classification Codes

Classification Code

  • Drug / Therapeutic Agent

Superlist Classification Code

  • DEA Schedule III
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Names and Synonyms

Name of Substance

  • Benzphetamine hydrochloride [NF]

Synonyms

  • (+)-Benzphetamine hydrochloride
  • (+)-N-Benzyl-N,alpha-dimethylphenethylamine hydrochloride
  • Benzphetamine HCl
  • Benzphetamine hydrochloride
  • d-Benzphetamine hydrochloride
  • Didrex
  • EINECS 226-489-2
  • Inapetyl
  • NSC 10937
  • U 0441
  • U-0441
  • UNII-43DWT87QT7

Systematic Names

  • (+)-N-Benzyl-N,alpha-dimethylphenethylamine hydrochloride
  • Benzeneethanamine, N,alpha-dimethyl-N-(phenylmethyl)-, hydrochloride, (+)- (9CI)
  • Benzeneethanamine, N,alpha-dimethyl-N-(phenylmethyl)-, hydrochloride, (alphaS)-
  • Benzphetamine hydrochloride
  • Phenethylamine, N-benzyl-N,alpha-dimethyl-, hydrochloride, (+)-

Superlist Names

  • Benzphetamine
  • Benzphetamine hydrochloride
  • DEA No. 1228
  • Didrex

Registry Numbers

CAS Registry Number

  • 5411-22-3

FDA UNII

  • 43DWT87QT7

System Generated Number

  • 0005411223

Molecular Formulas

Molecular Formula

  • C17-H21-N.Cl-H

Molecular Formula Fragments

  • C17-H21-N
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C17H21N.ClH/c1-15(13-16-9-5-3-6-10-16)18(2)14-17-11-7-4-8-12-17;/h3-12,15H,13-14H2,1-2H3;1H/t15-;/m0./s1

InChIKey

ANFSNXAXVLRZCG-RSAXXLAASA-N

Smiles

Cl.C[C@@H](Cc1ccccc1)N(C)Cc2ccccc2

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 102mg/kg (102mg/kg)   Toxicology and Applied Pharmacology. Vol. 6, Pg. 15, 1964.
mouse LD50 oral 227mg/kg (227mg/kg)   Current Therapeutic Research, Clinical & Experimental. Vol. 2, Pg. 33, 1960.
rat LD50 oral 160mg/kg (160mg/kg)   Current Therapeutic Research, Clinical & Experimental. Vol. 2, Pg. 33, 1960.