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Substance Name: Liothyronine sodium [USP:BAN:JAN]
RN: 55-06-1
UNII: GCA9VV7D2N
InChIKey: SBXXSUDPJJJJLC-YDALLXLXSA-M

Notes

  • A metabolite of THYROXINE, formed by the peripheral enzymatic monodeiodination of T4 at the 5 position of the inner ring of the iodothyronine nucleus.
  • A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.

Molecular Formula

  • C15-H12-I3-N-O4.Na

Molecular Weight

  • 672.945
 

Classification Code

  • Thyroid Hormone

Names and Synonyms

Name of Substance

  • Liothyronine sodium [USP:BAN:JAN]

Synonyms

  • 3,3',5-Triiodo-L-thyronine sodium
  • 3,3',5-Triiodo-L-thyronine sodium salt
  • 3,3',5-Triiodothyronine sodium salt
  • Basoprocin
  • Cynomel
  • Cytomel
  • Cytomel sodium
  • EINECS 200-223-5
  • Ibiothyron
  • L-3,3',5-Triiodothyronine sodium salt
  • L-Thyroxine monosodium salt
  • L-Triiodothyronine sodium salt
  • Liothyronine sodium
  • Monosodium L-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)alanine
  • NSC 80774
  • Ro thyronine
  • Sodium 3,3',5-triiodo-L-thyronine
  • Sodium 3,5,3'-triiodo-L-thyronine
  • Sodium 3,5,3'-triiodothyronine
  • Sodium L-3,5,3'-triiodothyronine
  • Sodium liothyronine
  • Sodium T3
  • Sodium triiodothyronine
  • Sodium triiodothyronine, L-
  • Sodium triiodotironine
  • Sodium-L-triiodothyronine
  • T3 sodium salt
  • Tertroxin
  • Triiodothyronine sodium
  • Triostat
  • UNII-GCA9VV7D2N

Systematic Names

  • Alanine, 3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)-, monosodium salt, L- (8CI)
  • L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-, monosodium salt
  • Liothyronine sodium

Registry Numbers

CAS Registry Number

  • 55-06-1

FDA UNII

  • GCA9VV7D2N

System Generated Number

  • 0000055061

Molecular Formulas

Molecular Formula

  • C15-H12-I3-N-O4.Na

Molecular Formula Fragments

  • C15-H12-I3-N-O4
  • COMPONENT
  • Na

Structure Descriptors

InChI

1S/C15H12I3NO4.Na/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22;/h1-4,6,12,20H,5,19H2,(H,21,22);/q;+1/p-1/t12-;/m0./s1

InChIKey

SBXXSUDPJJJJLC-YDALLXLXSA-M

Smiles

c1(Oc2cc(c(O)cc2)I)c(cc(C[C@@H](C(=O)[O-])N)cc1I)I.[Na+]