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Substance Name: Pheniprazine [INN:BAN]
RN: 55-52-7
UNII: 37VKD7067M
InChIKey: VXTWEDPZMSVFEF-UHFFFAOYSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Human Data
  • Mutation Data

Molecular Formula

  • C9-H14-N2

Molecular Weight

  • 150.224
 
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Names and Synonyms

Results Name

  • Pheniprazine [INN:BAN]

Name of Substance

  • Pheniprazine
  • Pheniprazine [INN:BAN]

Synonyms

  • (alpha-Methylphenethyl)hydrazine
  • 1-Phenyl-2-hydrazinopropane
  • 2-Hydrazino-1-phenylpropane
  • 2-Hydrazinopropylbenzene
  • beta-Phenylisopropylhydrazine
  • Catron
  • Dicatron
  • EINECS 200-236-6
  • Fenilisopropilidrazina
  • Feniprazina
  • Feniprazina [INN-Spanish]
  • Feniprazyne
  • Feniprazyne [Polish]
  • P 1142
  • Pheniprazine
  • Pheniprazinum
  • Pheniprazinum [INN-Latin]
  • Phenizine
  • PIH
  • UNII-37VKD7067M

Systematic Names

  • Hydrazine, (1-methyl-2-phenylethyl)- (9CI)
  • Hydrazine, (alpha-methylphenethyl)-
  • Pheniprazine

Registry Numbers

CAS Registry Number

  • 55-52-7

FDA UNII

  • 37VKD7067M

System Generated Number

  • 0000055527

Structure Descriptors

InChI

1S/C9H14N2/c1-8(11-10)7-9-5-3-2-4-6-9/h2-6,8,11H,7,10H2,1H3

InChIKey

VXTWEDPZMSVFEF-UHFFFAOYSA-N

Smiles

c1(C[C@@H](NN)C)ccccc1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intravenous 30mg/kg (30mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE
Journal of Pharmacology and Experimental Therapeutics. Vol. 128, Pg. 7, 1960.
cat LDLo subcutaneous 30mg/kg (30mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE

GASTROINTESTINAL: NAUSEA OR VOMITING

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Journal of Pharmacology and Experimental Therapeutics. Vol. 128, Pg. 7, 1960.
man TDLo unreported 117mg/kg/2.5Y (117mg/kg) SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
British Medical Journal. Vol. 1, Pg. 331, 1963.
mouse LD50 intraperitoneal 48mg/kg (48mg/kg) BEHAVIORAL: ANTICONVULSANT Japanese Journal of Pharmacology. Vol. 13, Pg. 186, 1963.
mouse LD50 intravenous 12100ug/kg (12.1mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 352, 1962.
mouse LD50 oral 121mg/kg (121mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 166, Pg. 449, 1967.
mouse LD50 subcutaneous 95mg/kg (95mg/kg)   Annals of the New York Academy of Sciences. Vol. 80, Pg. 568, 1959.
rat LD50 intraperitoneal 40mg/kg (40mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 353, 1972.
rat LD50 intravenous 44mg/kg (44mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 353, 1972.
rat LD50 oral 34mg/kg (34mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 353, 1972.
rat LD50 subcutaneous 45mg/kg (45mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 353, 1972.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point < 25 deg C   EXP
log P (octanol-water) 1.390 (none)   EST
Atmospheric OH Rate Constant 9.14E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.