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Substance Name: Arbaprostil [USAN:INN]
RN: 55028-70-1
UNII: M6B59S6MEF
InChIKey: XSGQFHNPNWBVPT-VFXMVCAWSA-N

Note

  • A synthetic prostaglandin E analog that protects the gastric mucosa, prevents ulceration, and promotes healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inhibitor of pancreatic function and can inhibit the growth of experimental tumors.

Molecular Formula

  • C21-H34-O5

Molecular Weight

  • 366.4946
 

Classification Codes

  • Anti-Ulcer Agents
  • Antisecretory (Gastric)
  • Gastrointestinal Agents
  • Human Data
  • Reproductive Effect
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Names and Synonyms

Name of Substance

  • Arbaprostil
  • Arbaprostil [USAN:INN]

MeSH Heading

  • Arbaprostil

Synonyms

  • (15R)-15-Methylprostaglandin E2
  • (5A,11alpha,13E,15R)-11,15-Dihydroxy-15-methyl-9-oxo-5,13-prostadiensaeure
  • (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3R)-(3-hydroxy-3-methyl-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid
  • 15(R)-15-Methyl prostaglandin E2
  • 15(R)-Methylprostaglandin E2
  • Arbacet
  • Arbaprostil
  • Arbaprostilo
  • Arbaprostilo [INN-Spanish]
  • Arbaprostilum
  • Arbaprostilum [INN-Latin]
  • CCRIS 1921
  • U 42,842
  • U 42-842
  • U 42842
  • UNII-M6B59S6MEF

Systematic Names

  • Araprostil
  • Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-15-methyl-9-oxo-, (5Z,11alpha,13E,15R)-

Registry Numbers

CAS Registry Number

  • 55028-70-1

FDA UNII

  • M6B59S6MEF

System Generated Number

  • 0055028701

Structure Descriptors

InChI

1S/C21H34O5/c1-3-4-9-13-21(2,26)14-12-17-16(18(22)15-19(17)23)10-7-5-6-8-11-20(24)25/h5,7,12,14,16-17,19,23,26H,3-4,6,8-11,13,15H2,1-2H3,(H,24,25)/b7-5-,14-12+/t16-,17-,19-,21-/m1/s1

InChIKey

XSGQFHNPNWBVPT-VFXMVCAWSA-N

Smiles

CCCCC[C@@](C)(O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(=O)O