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Substance Name: Nalmefene [USAN:INN:BAN]
RN: 55096-26-9
UNII: TOV02TDP9I
InChIKey: WJBLNOPPDWQMCH-MBPVOVBZSA-N

Classification Codes

  • Antagonist (to Narcotics)
  • Central Nervous System Agents
  • Narcotic Antagonists
  • Peripheral Nervous System Agents
  • Sensory System Agents

Molecular Formula

  • C21-H25-N-O3

Molecular Weight

  • 339.4325
 

Names and Synonyms

Name of Substance

  • Nalmefene
  • Nalmefene [USAN:INN:BAN]

Synonyms

  • (5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinon-3,14-diol
  • 17-(Cyclopropylmethyl)-4,5alpha-epoxy-6-methylenemorphinan-3,14-diol
  • 6-Desoxy-6-methylenenaltrexone
  • 9a-(Cyclopropylmethyl)-4,5alpha-epoxy-6-methylen-3,14-morphinandiol
  • HSDB 6761
  • JF 1
  • JF-1
  • Nalmefene
  • Nalmefeno
  • Nalmefeno [INN-Spanish]
  • Nalmefenum
  • Nalmefenum [INN-Latin]
  • Nalmetrene
  • Nalmetreno
  • Nalmetreno [INN-Spanish]
  • Nalmetrenum
  • Nalmetrenum [INN-Latin]
  • ORF 11676
  • UNII-TOV02TDP9I

Systematic Name

  • Morphinan-3,14-diol, 17-(cyclopropylmethyl)-4,5-epoxy-6-methylene-, (5alpha)-

Registry Numbers

CAS Registry Number

  • 55096-26-9

FDA UNII

  • TOV02TDP9I

Related Registry Number

  • 58895-64-0 (hydrochloride)

System Generated Number

  • 0055096269

Structure Descriptors

InChI

1S/C21H25NO3/c1-12-6-7-21(24)16-10-14-4-5-15(23)18-17(14)20(21,19(12)25-18)8-9-22(16)11-13-2-3-13/h4-5,13,16,19,23-24H,1-3,6-11H2/t16-,19+,20+,21-/m1/s1

InChIKey

WJBLNOPPDWQMCH-MBPVOVBZSA-N

Smiles

Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]56[C@@H](Oc1c25)C(=C)CC[C@@]36O

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 188-190 deg C   EXP
log P (octanol-water) 2.660 (none)   EST
Water Solubility 140 mg/L 25 EST
Vapor Pressure 5.70E-14 mm Hg 25 EST
Henry's Law Constant 1.82E-16 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 3.18E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.