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Substance Name: Sanguinarium chloride [USAN:INN]
RN: 5578-73-4
UNII: B8Z8J4400H
InChIKey: GIZKAXHWLRYMLE-UHFFFAOYSA-M

Classification Codes

  • Anti-Inflammatory
  • Antifungal
  • Antimicrobial

Molecular Formula

  • C20-H14-N-O4.Cl

Molecular Weight

  • 367.7866
 
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Names and Synonyms

Name of Substance

  • Sanguinarium chloride [USAN:INN]

Synonyms

  • (1,3)Benzodioxolo(5,6-c)-1,3-dioxolo(4,5-i)phenanthridinium, 13-methyl-, chloride
  • Sanguinarine chloride
  • Sanguinarine hydrochloride
  • Sanguinarium chloride
  • UNII-B8Z8J4400H
  • Viadent

Systematic Names

  • (1,3)Benzodioxolo(5,6-c)-1,3-dioxolo(4,5-i)phenanthridinium, 13-methyl-, chloride
  • Sanguinarine, chloride

Registry Numbers

CAS Registry Number

  • 5578-73-4

FDA UNII

  • B8Z8J4400H

Related Registry Number

  • 2447-54-3 (Parent)

System Generated Number

  • 0005578734

Molecular Formulas

Molecular Formula

  • C20-H14-N-O4.Cl

Molecular Formula Fragments

  • C20-H14-N-O4
  • Cl
  • COMPONENT

Structure Descriptors

InChI

1S/C20H14NO4.ClH/c1-21-8-15-12(4-5-16-20(15)25-10-22-16)13-3-2-11-6-17-18(24-9-23-17)7-14(11)19(13)21;/h2-8H,9-10H2,1H3;1H/q+1;/p-1

InChIKey

GIZKAXHWLRYMLE-UHFFFAOYSA-M

Smiles

[Cl-].C[n+]1cc2c3OCOc3ccc2c4ccc5cc6OCOc6cc5c14

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 15900ug/kg (15.9mg/kg)   Planta Medica. Vol. 43, Pg. 161, 1981.
mouse LD50 subcutaneous 102mg/kg (102mg/kg)   Planta Medica. Vol. 43, Pg. 161, 1981.
rat LD50 intravenous 29mg/kg (29mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BEHAVIORAL: ATAXIA
Journal of Toxicology and Environmental Health. Vol. 20, Pg. 199, 1987.
rat LD50 oral 1658mg/kg (1658mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Journal of Toxicology and Environmental Health. Vol. 20, Pg. 199, 1987.
rat LDLo intraperitoneal 20mg/kg (20mg/kg)   Nature. Vol. 162, Pg. 265, 1948.