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Substance Name: Miroprofen [INN]
RN: 55843-86-2
UNII: S00I5XG484
InChIKey: OJGQFYYLKNCIJD-UHFFFAOYSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Reproductive Effect

Molecular Formula

  • C16-H14-N2-O2

Molecular Weight

  • 266.299
 
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Names and Synonyms

Name of Substance

  • Miroprofen
  • Miroprofen [INN]

Synonyms

  • 1-Methoxy-3-(2-nitro-1-imidazolyl)-2-propanol
  • 2-(4-(Imidazo(1,2-a)pyridin-2-yl)phenyl)propionic acid
  • 2-(p-(2-Imidazo(1,2-a)pyridiyl)phenyl)propionsaeure
  • 2-(p-(2-Imidazo(1,2-a)pyridiyl)phenyl)propionsaeure [German]
  • 2-(p-(2-Imidazo(1,2-a)pyridyl)phenyl)propionic acid
  • 4-Imidazo(1,2-a)pyridin-2-yl-alpha-methylbenzeneacetic acid
  • alpha-(Methoxymethyl)-2-nitroimidazole-1-ethanol
  • Antopen
  • BRN 0888858
  • Miroprofen
  • Miroprofene
  • Miroprofene [INN-French]
  • Miroprofeno
  • Miroprofeno [INN-Spanish]
  • Miroprofenum
  • Miroprofenum [INN-Latin]
  • NSC 261037
  • p-Imidazo(1,2-a)pyridin-2-ylhydratropic acid
  • Propionic acid, 2-(4-(imidazo(1,2-a)pyridin-2-yl)phenyl)-
  • Ro 07-0582
  • Ro-07-0582
  • UNII-S00I5XG484
  • Y 9213
  • Y-9213

Systematic Names

  • Benzeneacetic acid, 4-imidazo(1,2-a)pyridin-2-yl-alpha-methyl-
  • p-Imidazo(1,2-a)pyridin-2-ylhydratropic acid
  • Propionic acid, 2-(p-(imidazo(1,2-a)pyridin-2-yl)phenyl)-

Registry Numbers

CAS Registry Number

  • 55843-86-2

FDA UNII

  • S00I5XG484

System Generated Number

  • 0055843862

Structure Descriptors

InChI

1S/C16H14N2O2/c1-11(16(19)20)12-5-7-13(8-6-12)14-10-18-9-3-2-4-15(18)17-14/h2-11H,1H3,(H,19,20)

InChIKey

OJGQFYYLKNCIJD-UHFFFAOYSA-N

Smiles

c1ccn2c(c1)nc(c1ccc(cc1)[C@@H](C)C(=O)O)c2

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 696mg/kg (696mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 993, 1981.
mouse LD50 intraperitoneal 696mg/kg (696mg/kg) BLOOD: APLASTIC ANEMIA

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 993, 1981.
mouse LD50 oral 570mg/kg (570mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 2102, 1978.
mouse LD50 subcutaneous 687mg/kg (687mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BLOOD: APLASTIC ANEMIA
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 993, 1981.
rat LD50 intraperitoneal 365mg/kg (365mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 993, 1981.
rat LD50 intraperitoneal 365mg/kg (365mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BLOOD: APLASTIC ANEMIA
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 993, 1981.
rat LD50 oral 292mg/kg (292mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 993, 1981.
rat LD50 oral 292mg/kg (292mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BLOOD: APLASTIC ANEMIA
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 993, 1981.
rat LD50 subcutaneous 372mg/kg (372mg/kg) BLOOD: APLASTIC ANEMIA

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 993, 1981.