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Substance Name: Betamethasone dipropionate [USAN:USP:JAN]
RN: 5593-20-4
UNII: 826Y60901U
InChIKey: CIWBQSYVNNPZIQ-XYWKZLDCSA-N
Classification Codes
- Anti-Inflammatory Agents
- Drug / Therapeutic Agent
- Glucocorticoid
- Hormone
- Reproductive Effect
Molecular Formula
- C28-H37-F-O7
Molecular Weight
- 504.5913
- All
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
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Names and Synonyms
Name of Substance
- Betamethasone dipropionate [USAN:USP:JAN]
- Betamethasone-17,21-dipropionate
Synonyms
- 9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate
- Alphatrex
- beta-Methasone 17,21-dipropionate
- Betamethasone 17,21-dipropionate
- Betamethasone dipropionate
- BRN 3638108
- Diproderm
- Diprolene
- Diprolene AF
- Diprosis
- Diprosone
- EINECS 227-005-2
- Maxivate
- NSC 758415
- Psorion
- Rinderon DP
- S 3440
- S-3440
- Sch 11460
- Sernivo
- UNII-826Y60901U
Systematic Names
- 9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-di(propionate)
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-16-beta-methyl-, 17,21-dipropionate
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11beta,16beta)
Mixture Names
- Alphatrex
- Betasone (Veterinary)
- Lotrisone
Registry Numbers
CAS Registry Number
- 5593-20-4
FDA UNII
- 826Y60901U
System Generated Number
- 0005593204
Structure Descriptors
InChI
InChI=1S/C28H37FO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1InChIKey
CIWBQSYVNNPZIQ-XYWKZLDCSA-NSmiles
CCC(=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 103mg/kg (103mg/kg) | Drugs in Japan Vol. 6, Pg. 753, 1982. | |
mouse | LD50 | oral | > 5gm/kg (5000mg/kg) | BEHAVIORAL: ANTIPSYCHOTIC SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 29, Pg. 153, 1973. |
mouse | LD50 | subcutaneous | 78100ug/kg (78.1mg/kg) | Drugs in Japan Vol. 6, Pg. 753, 1982. | |
rat | LD50 | intraperitoneal | > 4gm/kg (4000mg/kg) | Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 29, Pg. 153, 1973. | |
rat | LD50 | oral | > 4gm/kg (4000mg/kg) | Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 29, Pg. 153, 1973. | |
rat | LD50 | subcutaneous | > 4gm/kg (4000mg/kg) | Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 29, Pg. 153, 1973. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 232 dec | deg C | EXP | |
log P (octanol-water) | 4.07 | (none) | EXP | |
Water Solubility | 0.724 | mg/L | 25 | EST |
Vapor Pressure | 9.01E-14 | mm Hg | 25 | EST |
Henry's Law Constant | 1.47E-15 | atm-m3/mole | 25 | EST |
Atmospheric OH Rate Constant | 6.88E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.