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Substance Name: Carbon tetrachloride [BSI:ISO]
RN: 56-23-5
UNII: CL2T97X0V0
InChIKey: VZGDMQKNWNREIO-UHFFFAOYSA-N
Note
- A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)
Molecular Formula
- C-Cl4
Molecular Weight
- 153.823
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Agricultural Chemical
- Drug / Therapeutic Agent
- Fungicide, Bactericide, Wood Preservative
- Human Data
- Insecticide
- Mutation Data
- Reproductive Effect
- Skin / Eye Irritant
- Tumor Data
Superlist Classification Codes
- 2007 CERCLA Priority List, Rank: 47
- 2011 CERCLA Priority List, Rank: 50
- Overall Carcinogenic Evaluation: Group 2B
- Reasonably Anticipated to be a Carcinogen
- Reportable Quantity (RQ) = 10 lb
- TWA (5 ppm); STEL (10 ppm); skin; Suspected human carcinogen
- TWA 10 ppm; Ceiling 25 ppm, peak 300 ppm in 5 min in any 4 hours
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Names and Synonyms
Results Name
- Carbon tetrachloride [BSI:ISO]
Name of Substance
- Carbon tetrachloride [BSI:ISO]
- Carbon tetrachloride [NF]
MeSH Heading
- Carbon tetrachloride
Synonyms
- AI3-04705
- Benzinoform
- Carbon chloride (CCl4)
- Carbon tet
- Carbon tetrachloride
- Carbona
- Caswell No. 164
- CC m0
- CCRIS 123
- Chlorid uhlicity
- Chlorid uhlicity [Czech]
- Czterochlorek wegla
- Czterochlorek wegla [Polish]
- EC 200-262-8
- EINECS 200-262-8
- ENT 27164
- ENT 4,705
- EPA Pesticide Chemical Code 016501
- Fasciolin
- Flukoids
- Freon 10
- Halon 1040
- HSDB 53
- Methane tetrachloride
- Methane, tetrachloro-
- Necatorina
- Necatorine
- NSC 97063
- Perchloromethane
- R 10
- R 10 (Refrigerant)
- RCRA waste number U211
- Tetrachloorkoolstof
- Tetrachloorkoolstof [Dutch]
- Tetrachloormetaan
- Tetrachlorkohlenstoff, tetra
- Tetrachlorkohlenstoff, tetra [German]
- Tetrachlormethan
- Tetrachlormethan [German]
- Tetrachloromethane
- Tetrachlorure de carbone
- Tetrachlorure de carbone [French]
- Tetrachlorure de carbone [ISO-French]
- Tetraclorometano
- Tetraclorometano [Italian]
- Tetracloruro di carbonio
- Tetracloruro di carbonio [Italian]
- Tetrafinol
- Tetraform
- Tetrasol
- UNII-CL2T97X0V0
- Univerm
- Vermoestricid
Systematic Names
- Carbon tetrachloride
- Methane, tetrachloro-
Superlist Names
- Carbon tetrachloride
- Carbon tetrachloride [UN1846] [Poison]
- Methane, tetrachloro-
- RCRA waste no. U211
- Tetrachloromethane
- UN1846
Registry Numbers
CAS Registry Number
- 56-23-5
FDA UNII
- CL2T97X0V0
System Generated Number
- 0000056235
Structure Descriptors
InChI
InChI=1S/CCl4/c2-1(3,4)5InChIKey
VZGDMQKNWNREIO-UHFFFAOYSA-NSmiles
ClC(Cl)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LCLo | inhalation | 38110ppm/2H (38110ppm) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1405, 1935. | |
cat | LDLo | subcutaneous | 300mg/kg (300mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BLOOD: HEMORRHAGE LIVER: FATTY LIVER DEGERATION | Journal of Pharmacology and Experimental Therapeutics. Vol. 63, Pg. 153, 1938. |
chicken | LD50 | intraperitoneal | 4497mg/kg (4497mg/kg) | GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE GASTROINTESTINAL: OTHER CHANGES | British Veterinary Journal. Vol. 127, Pg. 304, 1971. |
dog | LCLo | inhalation | 14620ppm/8H (14620ppm) | BEHAVIORAL: GENERAL ANESTHETIC VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION | National Institutes of Health, Bulletin. Vol. 191, Pg. 1, 1949. |
dog | LD50 | intraperitoneal | 1500mg/kg (1500mg/kg) | LIVER: LIVER FUNCTION TESTS IMPAIRED | Toxicology and Applied Pharmacology. Vol. 10, Pg. 119, 1967. |
dog | LDLo | intravenous | 125mg/kg (125mg/kg) | Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934. | |
dog | LDLo | oral | 1gm/kg (1000mg/kg) | Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934. | |
frog | LCLo | inhalation | 58gm/m3 (58000mg/m3) | Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 97, Pg. 86, 1923. | |
guinea pig | LCLo | inhalation | 20000ppm/2H (20000ppm) | Fluorine Chemistry Reviews. Vol. 1, Pg. 197, 1967. | |
guinea pig | LD50 | oral | 5760mg/kg (5760mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(1), Pg. 32, 1968. | |
guinea pig | LD50 | skin | > 9400uL/kg (9.4mL/kg) | Toxicology and Applied Pharmacology. Vol. 7, Pg. 559, 1965. | |
human | LCLo | inhalation | 1000ppm (1000ppm) | Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 198, 1966. | |
human | LCLo | inhalation | 5pph/5M (50000ppm) | Tabulae Biologicae. Vol. 3, Pg. 231, 1933. | |
human | TCLo | inhalation | 20ppm (20ppm) | GASTROINTESTINAL: NAUSEA OR VOMITING | "Chemistry of Industrial Toxicology," 2nd ed., Elkins, H.B., New York, John Wiley & Sons, Inc., 1959Vol. 2, Pg. 136, 1959. |
human | TCLo | inhalation | 45ppm/3D (45ppm) | BEHAVIORAL: ANOREXIA (HUMAN GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Lancet. Vol. 1, Pg. 360, 1960. |
human | TCLo | inhalation | 317ppm/30M (317ppm) | GASTROINTESTINAL: NAUSEA OR VOMITING | JAMA, Journal of the American Medical Association. Vol. 103, Pg. 962, 1934. |
mammal (species unspecified) | LC50 | inhalation | 34500mg/m3 (34500mg/m3) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 24(3), Pg. 17, 1980. | |
mammal (species unspecified) | LD50 | oral | 6gm/kg (6000mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988. | |
man | LDLo | oral | 429mg/kg (429mg/kg) | LUNGS, THORAX, OR RESPIRATION: CYANOSIS KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS CARDIAC: CHANGE IN RATE | Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. Vol. 19, Pg. 781, 1973. |
man | LDLo | unreported | 93mg/kg (93mg/kg) | "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970. | |
man | TDLo | oral | 1700mg/kg (1700mg/kg) | BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES GASTROINTESTINAL: OTHER CHANGES | South African Medical Journal. Vol. 49, Pg. 635, 1975. |
mouse | LC50 | inhalation | 9526ppm/8H (9526ppm) | Journal of Industrial Hygiene and Toxicology. Vol. 29, Pg. 382, 1947. | |
mouse | LD50 | intraperitoneal | 572mg/kg (572mg/kg) | Pharmacologist. Vol. 10, Pg. 172, 1968. | |
mouse | LD50 | oral | 8263mg/kg (8263mg/kg) | Journal of Pharmacy and Pharmacology. Vol. 3, Pg. 169, 1951. | |
mouse | LD50 | subcutaneous | 31gm/kg (31000mg/kg) | BEHAVIORAL: ATAXIA BEHAVIORAL: SLEEP | Journal of Pharmacology and Experimental Therapeutics. Vol. 123, Pg. 224, 1958. |
rabbit | LD50 | intravenous | 5840mg/kg (5840mg/kg) | BEHAVIORAL: EXCITEMENT BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Zentralblatt fuer Allgemeine Pathologie und Pathologische Anatomie. Vol. 118, Pg. 305, 1974. |
rabbit | LD50 | oral | 5760mg/kg (5760mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(1), Pg. 32, 1968. | |
rabbit | LD50 | skin | > 20gm/kg (20000mg/kg) | Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 712, 1992. | |
rabbit | LDLo | intraperitoneal | 477mg/kg (477mg/kg) | Gastroenterology. Vol. 71, Pg. 118, 1976. | |
rabbit | LDLo | subcutaneous | 3gm/kg (3000mg/kg) | Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934. | |
rat | LC50 | inhalation | 8000ppm/4H (8000ppm) | Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 16, 1974. | |
rat | LD50 | intraperitoneal | 1500uL/kg (1.5mL/kg) | U.S. Atomic Energy Commission, University of Rochester, Research and Development Reports. Vol. MDDC-1715, | |
rat | LD50 | oral | 2350mg/kg (2350mg/kg) | Archives of Toxicology. Vol. 54, Pg. 275, 1983. | |
rat | LD50 | skin | 5070mg/kg (5070mg/kg) | Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 16, 1978. | |
rat | LDLo | intratracheal | 90mg/kg (90mg/kg) | National Technical Information Service. Vol. OTS0520615, | |
women | TDLo | oral | 1800mg/kg (1800mg/kg) | BEHAVIORAL: ANTIPSYCHOTIC BEHAVIORAL: COMA SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE | Texas Medicine. Vol. 69, Pg. 86, 1973. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | -2.30E+01 | deg C | EXP | |
Boiling Point | 76.8 | deg C | EXP | |
log P (octanol-water) | 2.83 | (none) | EXP | |
Water Solubility | 793 | mg/L | 25 | EXP |
Vapor Pressure | 115 | mm Hg | 25 | EXP |
Henry's Law Constant | 0.0276 | atm-m3/mole | 25 | EXP |
Atmospheric OH Rate Constant | 1.20E-16 | cm3/molecule-sec | 25 | EXP |
Physical property data is provided to ChemIDplus by SRC, Inc.