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Substance Name: Carbon tetrachloride [BSI:ISO]
RN: 56-23-5
UNII: CL2T97X0V0
InChIKey: VZGDMQKNWNREIO-UHFFFAOYSA-N

Note

  • A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)

Molecular Formula

  • C-Cl4

Molecular Weight

  • 153.823
 

Classification Codes

Classification Codes

  • Agricultural Chemical
  • Drug / Therapeutic Agent
  • Fungicide, Bactericide, Wood Preservative
  • Human Data
  • Insecticide
  • Mutation Data
  • Reproductive Effect
  • Skin / Eye Irritant
  • Tumor Data

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 47
  • 2011 CERCLA Priority List, Rank: 50
  • Overall Carcinogenic Evaluation: Group 2B
  • Reasonably Anticipated to be a Carcinogen
  • Reportable Quantity (RQ) = 10 lb
  • TWA (5 ppm); STEL (10 ppm); skin; Suspected human carcinogen
  • TWA 10 ppm; Ceiling 25 ppm, peak 300 ppm in 5 min in any 4 hours

Names and Synonyms

Results Name

  • Carbon tetrachloride [BSI:ISO]

Name of Substance

  • Carbon tetrachloride [BSI:ISO]
  • Carbon tetrachloride [NF]

MeSH Heading

  • Carbon tetrachloride

Synonyms

  • AI3-04705
  • Benzinoform
  • Carbon chloride (CCl4)
  • Carbon tet
  • Carbon tetrachloride
  • Carbona
  • Caswell No. 164
  • CC m0
  • CCRIS 123
  • Chlorid uhlicity
  • Chlorid uhlicity [Czech]
  • Czterochlorek wegla
  • Czterochlorek wegla [Polish]
  • EC 200-262-8
  • EINECS 200-262-8
  • ENT 27164
  • ENT 4,705
  • EPA Pesticide Chemical Code 016501
  • Fasciolin
  • Flukoids
  • Freon 10
  • Halon 1040
  • HSDB 53
  • Methane tetrachloride
  • Methane, tetrachloro-
  • Necatorina
  • Necatorine
  • NSC 97063
  • Perchloromethane
  • R 10
  • R 10 (Refrigerant)
  • RCRA waste number U211
  • Tetrachloorkoolstof
  • Tetrachloorkoolstof [Dutch]
  • Tetrachloormetaan
  • Tetrachlorkohlenstoff, tetra
  • Tetrachlorkohlenstoff, tetra [German]
  • Tetrachlormethan
  • Tetrachlormethan [German]
  • Tetrachloromethane
  • Tetrachlorure de carbone
  • Tetrachlorure de carbone [French]
  • Tetrachlorure de carbone [ISO-French]
  • Tetraclorometano
  • Tetraclorometano [Italian]
  • Tetracloruro di carbonio
  • Tetracloruro di carbonio [Italian]
  • Tetrafinol
  • Tetraform
  • Tetrasol
  • UNII-CL2T97X0V0
  • Univerm
  • Vermoestricid

Systematic Names

  • Carbon tetrachloride
  • Methane, tetrachloro-

Superlist Names

  • Carbon tetrachloride
  • Carbon tetrachloride [UN1846] [Poison]
  • Methane, tetrachloro-
  • RCRA waste no. U211
  • Tetrachloromethane
  • UN1846

Registry Numbers

CAS Registry Number

  • 56-23-5

FDA UNII

  • CL2T97X0V0

System Generated Number

  • 0000056235

Structure Descriptors

InChI

1S/CCl4/c2-1(3,4)5

InChIKey

VZGDMQKNWNREIO-UHFFFAOYSA-N

Smiles

C(Cl)(Cl)(Cl)Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LCLo inhalation 38110ppm/2H (38110ppm)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1405, 1935.
cat LDLo subcutaneous 300mg/kg (300mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

BLOOD: HEMORRHAGE

LIVER: FATTY LIVER DEGERATION
Journal of Pharmacology and Experimental Therapeutics. Vol. 63, Pg. 153, 1938.
chicken LD50 intraperitoneal 4497mg/kg (4497mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE

GASTROINTESTINAL: OTHER CHANGES
British Veterinary Journal. Vol. 127, Pg. 304, 1971.
dog LCLo inhalation 14620ppm/8H (14620ppm) BEHAVIORAL: GENERAL ANESTHETIC

VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION
National Institutes of Health, Bulletin. Vol. 191, Pg. 1, 1949.
dog LD50 intraperitoneal 1500mg/kg (1500mg/kg) LIVER: LIVER FUNCTION TESTS IMPAIRED Toxicology and Applied Pharmacology. Vol. 10, Pg. 119, 1967.
dog LDLo intravenous 125mg/kg (125mg/kg)   Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934.
dog LDLo oral 1gm/kg (1000mg/kg)   Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934.
frog LCLo inhalation 58gm/m3 (58000mg/m3)   Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 97, Pg. 86, 1923.
guinea pig LCLo inhalation 20000ppm/2H (20000ppm)   Fluorine Chemistry Reviews. Vol. 1, Pg. 197, 1967.
guinea pig LD50 oral 5760mg/kg (5760mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(1), Pg. 32, 1968.
guinea pig LD50 skin > 9400uL/kg (9.4mL/kg)   Toxicology and Applied Pharmacology. Vol. 7, Pg. 559, 1965.
human LCLo inhalation 1000ppm (1000ppm)   Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 198, 1966.
human LCLo inhalation 5pph/5M (50000ppm)   Tabulae Biologicae. Vol. 3, Pg. 231, 1933.
human TCLo inhalation 20ppm (20ppm) GASTROINTESTINAL: NAUSEA OR VOMITING "Chemistry of Industrial Toxicology," 2nd ed., Elkins, H.B., New York, John Wiley & Sons, Inc., 1959Vol. 2, Pg. 136, 1959.
human TCLo inhalation 45ppm/3D (45ppm) BEHAVIORAL: ANOREXIA (HUMAN

GASTROINTESTINAL: NAUSEA OR VOMITING

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Lancet. Vol. 1, Pg. 360, 1960.
human TCLo inhalation 317ppm/30M (317ppm) GASTROINTESTINAL: NAUSEA OR VOMITING JAMA, Journal of the American Medical Association. Vol. 103, Pg. 962, 1934.
mammal (species unspecified) LC50 inhalation 34500mg/m3 (34500mg/m3)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 24(3), Pg. 17, 1980.
mammal (species unspecified) LD50 oral 6gm/kg (6000mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988.
man LDLo oral 429mg/kg (429mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS

KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS

CARDIAC: CHANGE IN RATE
Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. Vol. 19, Pg. 781, 1973.
man LDLo unreported 93mg/kg (93mg/kg)   "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
man TDLo oral 1700mg/kg (1700mg/kg) BEHAVIORAL: TREMOR

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

GASTROINTESTINAL: OTHER CHANGES
South African Medical Journal. Vol. 49, Pg. 635, 1975.
mouse LC50 inhalation 9526ppm/8H (9526ppm)   Journal of Industrial Hygiene and Toxicology. Vol. 29, Pg. 382, 1947.
mouse LD50 intraperitoneal 572mg/kg (572mg/kg)   Pharmacologist. Vol. 10, Pg. 172, 1968.
mouse LD50 oral 8263mg/kg (8263mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 3, Pg. 169, 1951.
mouse LD50 subcutaneous 31gm/kg (31000mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: SLEEP
Journal of Pharmacology and Experimental Therapeutics. Vol. 123, Pg. 224, 1958.
rabbit LD50 intravenous 5840mg/kg (5840mg/kg) BEHAVIORAL: EXCITEMENT

BEHAVIORAL: COMA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Zentralblatt fuer Allgemeine Pathologie und Pathologische Anatomie. Vol. 118, Pg. 305, 1974.
rabbit LD50 oral 5760mg/kg (5760mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(1), Pg. 32, 1968.
rabbit LD50 skin > 20gm/kg (20000mg/kg)   Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 712, 1992.
rabbit LDLo intraperitoneal 477mg/kg (477mg/kg)   Gastroenterology. Vol. 71, Pg. 118, 1976.
rabbit LDLo subcutaneous 3gm/kg (3000mg/kg)   Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934.
rat LC50 inhalation 8000ppm/4H (8000ppm)   Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 16, 1974.
rat LD50 intraperitoneal 1500uL/kg (1.5mL/kg)   U.S. Atomic Energy Commission, University of Rochester, Research and Development Reports. Vol. MDDC-1715,
rat LD50 oral 2350mg/kg (2350mg/kg)   Archives of Toxicology. Vol. 54, Pg. 275, 1983.
rat LD50 skin 5070mg/kg (5070mg/kg)   Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 16, 1978.
rat LDLo intratracheal 90mg/kg (90mg/kg)   National Technical Information Service. Vol. OTS0520615,
women TDLo oral 1800mg/kg (1800mg/kg) BEHAVIORAL: ANTIPSYCHOTIC

BEHAVIORAL: COMA

SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE
Texas Medicine. Vol. 69, Pg. 86, 1973.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -2.30E+01 deg C   EXP
Boiling Point 76.8 deg C   EXP
log P (octanol-water) 2.83 (none)   EXP
Water Solubility 793 mg/L 25 EXP
Vapor Pressure 115 mm Hg 25 EXP
Henry's Law Constant 0.0276 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 1.20E-16 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.