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Substance Name: Glycine [USP:INN]
RN: 56-40-6
UNII: TE7660XO1C
InChIKey: DHMQDGOQFOQNFH-UHFFFAOYSA-N

Note

  • A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.

Molecular Formula

  • C2-H5-N-O2

Molecular Weight

  • 75.0665
 

Classification Codes

  • Component of Irrigating Solution
  • Glycine Agents
  • Mutation Data
  • Neurotransmitter Agents
  • TSCA Flag TP (Subject to the Proposed TSCA Section 4 Test Rule)

Names and Synonyms

Name of Substance

  • Aminoacetic acid
  • Glycine
  • Glycine [USP:INN]
  • Glycocoll

MeSH Heading

  • Glycine

Synonyms

  • 2-Aminoacetic acid
  • Acetic acid, amino-
  • Acide aminoacetique
  • Acide aminoacetique [INN-French]
  • Acido aminoacetico
  • Acido aminoacetico [INN-Spanish]
  • Acidum aminoaceticum
  • Acidum aminoaceticum [INN-Latin]
  • Aciport
  • AI3-04085
  • Aminoacetic acid
  • Aminoacetic acid 1.5% in plastic container
  • Aminoazijnzuur
  • Aminoethanoic acid
  • Amitone
  • CCRIS 5915
  • EC 200-272-2
  • EINECS 200-272-2
  • FEMA No. 3287
  • Glicina
  • Glicina [INN-Spanish]
  • Glicoamin
  • GLY (IUPAC abbrev)
  • Glycin
  • Glycine
  • Glycine 1.5% in plastic container
  • Glycine, non-medical
  • Glycinum
  • Glycinum [INN-Latin]
  • Glycocoll
  • Glycolixir
  • Glycosthene
  • Hampshire glycine
  • HSDB 495
  • L-Glycine
  • Leimzucker
  • NSC 25936
  • Padil
  • Sucre de gelatine
  • UNII-TE7660XO1C

Systematic Name

  • Glycine

Superlist Name

  • Glycine

Mixture Name

  • Corilin

Registry Numbers

CAS Registry Number

  • 56-40-6

FDA UNII

  • TE7660XO1C

Other Registry Numbers

  • 1119449-36-3
  • 1153953-88-8
  • 1173020-11-5
  • 1196157-78-4
  • 52955-63-2
  • 57678-19-0
  • 848646-45-7
  • 87867-94-5

Related Registry Numbers

  • 15743-44-9 (mono-potassium salt)
  • 17829-66-2 (cobalt salt)
  • 29728-27-6 (monoammonium salt)
  • 32817-15-5 (copper salt)
  • 33242-26-1 (calcium salt)
  • 35947-07-0 (calcium salt (2:1))
  • 513-29-1 (sulfate (3:1))
  • 6000-43-7 (hydrochloride)
  • 6000-44-8 (mono-hydrochloride salt)
  • 63183-41-5 (hydrochloride hydrogen carbonate)
  • 71295-98-2 (phosphate (1:1))
  • 7490-95-1 (hydrochloride (2:1)
  • 7490-95-1 (hydrochloride (2:1))

System Generated Number

  • 0000056406

Structure Descriptors

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChIKey

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Smiles

C(=O)(CN)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intravenous 3gm/kg (3000mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: FOOD INTAKE (ANIMAL)

BEHAVIORAL: ATAXIA
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 31, Pg. 306, 1942.
mouse LD50 intraperitoneal 4450mg/kg (4450mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 5, Pg. 1502, 1977.
mouse LD50 intravenous 2370mg/kg (2370mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 5, Pg. 1502, 1977.
mouse LD50 oral 4920mg/kg (4920mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 5, Pg. 1502, 1977.
mouse LD50 subcutaneous 5060mg/kg (5060mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 5, Pg. 1502, 1977.
rat LD50 intravenous 2600mg/kg (2600mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 5, Pg. 1502, 1977.
rat LD50 oral 7930mg/kg (7930mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 5, Pg. 1502, 1977.
rat LD50 subcutaneous 5200mg/kg (5200mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 5, Pg. 1502, 1977.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 262 dec deg C   EXP
pKa Dissociation Constant 2.366 (none) 20 EXP
log P (octanol-water) -3.21E+00 (none)   EXP
Water Solubility 2.49E+05 mg/L 25 EXP
Vapor Pressure 1.28E-07 mm Hg 25 EST
Henry's Law Constant 1.12E-09 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 2.80E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.