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Substance Name: Glutamic Acid [USAN:INN]
RN: 56-86-0
UNII: 3KX376GY7L
InChIKey: WHUUTDBJXJRKMK-VKHMYHEASA-N

Note

  • A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.

Molecular Formula

  • C5-H9-N-O4

Molecular Weight

  • 147.1291
 

Classification Codes

  • Human Data
  • Mutation Data

Names and Synonyms

Name of Substance

  • Glutamic acid
  • Glutamic Acid [USAN:INN]

MeSH Heading

  • Glutamic acid

Synonyms

  • 1-Aminopropane-1,3-dicarboxylic acid
  • 2-Aminopentanedioic acid
  • 2-Aminopentanedioic acid, (S)-
  • Acide glutamique
  • Acide glutamique [INN-French]
  • Acido glutamico
  • Acido glutamico [INN-Spanish]
  • Acidum glutamicum
  • Acidum glutamicum [INN-Latin]
  • Acidum glutaminicum
  • Aciglut
  • AI3-18472
  • alpha-Aminoglutaric acid
  • alpha-Aminoglutaric acid (VAN)
  • CCRIS 7314
  • D-Glutamiensuur
  • EC 200-293-7
  • EINECS 200-293-7
  • EPA Pesticide Chemical Code 374350
  • FEMA No. 3285
  • Glusate
  • Glutacid
  • Glutamate, L-
  • Glutamic acid
  • Glutamic acid (H-3)
  • Glutamic acid (VAN)
  • Glutamic acid, (S)-
  • Glutamicol
  • Glutamidex
  • Glutaminic acid
  • Glutaminic acid (VAN)
  • Glutaminol
  • Glutaton
  • HSDB 490
  • L-2-Aminoglutaric acid
  • L-Acido glutamico
  • L-Glutamic acid
  • L-Glutaminic acid
  • NSC 143503
  • Pentanedioic acid, 2-amino-, (S)-
  • UNII-3KX376GY7L

Systematic Names

  • Glutamic acid
  • L-Glutamic acid

Superlist Names

  • Glutamic acid, L-
  • L-Glutamic acid

Registry Numbers

CAS Registry Number

  • 56-86-0

FDA UNII

  • 3KX376GY7L

Other Registry Numbers

  • 10549-13-0
  • 138-16-9
  • 6899-05-4

Related Registry Numbers

  • 138-15-8 (unspecified hydrochloride)
  • 16690-92-9 (di-hydrochloride salt)
  • 19238-49-4 (unspecified calcium salt)
  • 19473-49-5 (mono-potassium salt)
  • 24595-14-0 (unspecified potassium salt)
  • 55695-80-2 (mono-lithium salt)
  • 7558-63-6 (mono-ammonium salt)

System Generated Number

  • 0000056860

Structure Descriptors

InChI

1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1

InChIKey

WHUUTDBJXJRKMK-VKHMYHEASA-N

Smiles

[C@H](CCC(=O)O)(C(=O)O)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human TDLo intravenous 117mg/kg (117mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING American Journal of the Medical Sciences. Vol. 214, Pg. 281, 1947.
human TDLo oral 71mg/kg (71mg/kg) BEHAVIORAL: HEADACHE Science. Vol. 163, Pg. 826, 1969.
rabbit LD50 oral > 2300mg/kg (2300mg/kg)   FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 42, 1970.
rat LD50 oral > 30gm/kg (30000mg/kg)   FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 42, 1970.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 224 dec deg C   EXP
pKa Dissociation Constant 2.23 (none) 0 EXP
log P (octanol-water) -3.69E+00 (none)   EXP
Water Solubility 8570 mg/L 25 EXP
Henry's Law Constant 1.47E-14 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 4.10E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.