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Substance Name: Zoliprofen [INN]
RN: 56355-17-0
UNII: J2GC047H27
InChIKey: RXZTWBVFHQLTBU-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C12-H11-N-O3-S

Molecular Weight

  • 249.289
 
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Names and Synonyms

Name of Substance

  • 480156-S
  • Zoliprofen [INN]

Synonyms

  • 2-(4-(2-Thiazolyloxy)phenyl)propionic acid
  • 480156 S
  • alpha-Methyl-4-(2-thiazolyloxy)benzeneacetic acid
  • BRN 1128230
  • CCRIS 1928
  • Propionic acid, 2-(p-((2-thiazolyl)oxy)phenyl)-
  • UNII-J2GC047H27
  • Zoliprofen
  • Zoliprofene
  • Zoliprofene [INN-French]
  • Zoliprofeno
  • Zoliprofeno [INN-Spanish]
  • Zoliprofenum
  • Zoliprofenum [INN-Latin]

Systematic Names

  • (+-)-p-(2-Thiazolyloxy)hydratropic acid
  • 2-(4-(2-Thiazolyloxy)phenyl)propionic acid
  • Benzeneacetic acid, alpha-methyl-4-(2-thiazolyloxy)-
  • Benzeneacetic acid, alpha-methyl-4-(2-thiazolyloxy)-, stereoisomer

Registry Numbers

CAS Registry Number

  • 56355-17-0

FDA UNII

  • J2GC047H27

System Generated Number

  • 0056355170

Structure Descriptors

InChI

1S/C12H11NO3S/c1-8(11(14)15)9-2-4-10(5-3-9)16-12-13-6-7-17-12/h2-8H,1H3,(H,14,15)

InChIKey

RXZTWBVFHQLTBU-UHFFFAOYSA-N

Smiles

c1cnc(Oc2ccc(cc2)[C@@H](C)C(=O)O)s1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 660mg/kg (660mg/kg) BEHAVIORAL: ANALGESIA Chemical and Pharmaceutical Bulletin. Vol. 31, Pg. 3424, 1983.
rat LD50 oral 135mg/kg (135mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 34, Pg. 280, 1984.