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Substance Name: Monoacetyldapsone
RN: 565-20-8
UNII: A4YKS8ULCN
InChIKey: WDOCBIHNYYQINH-UHFFFAOYSA-N

Note

  • Used in leprosy chemotherapy.

Classification Codes

  • Anti-Infective Agents
  • Drug / Therapeutic Agent

Molecular Formula

  • C14-H14-N2-O3-S

Molecular Weight

  • 290.342
 
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Names and Synonyms

Name of Substance

  • Monoacetyldapsone

Synonyms

  • 3-13-00-01286 (Beilstein Handbook Reference)
  • 4'-Sulfanilylacetanilide
  • Acetamide, N-(4-((4-aminophenyl)sulfonyl)phenyl)-
  • Acetyldapsone
  • BRN 2746651
  • CCRIS 5693
  • MADDS
  • Monoacetyldapsone
  • N-Acetyl-4,4'-diaminodiphenylsulfone
  • N-Acetyldapsone
  • NSC 27184
  • UNII-A4YKS8ULCN

Systematic Names

  • Acetamide, N-(4-((4-aminophenyl)sulfonyl)phenyl)- (9CI)
  • Acetanilide, 4'-sulfanilyl-
  • N-(4-((4-Aminophenyl)sulfonyl)phenyl)acetamide
  • N-Acetyl-4,4-diaminodiphenylsulfone

Registry Numbers

CAS Registry Number

  • 565-20-8

FDA UNII

  • A4YKS8ULCN

System Generated Number

  • 0000565208

Structure Descriptors

InChI

1S/C14H14N2O3S/c1-10(17)16-12-4-8-14(9-5-12)20(18,19)13-6-2-11(15)3-7-13/h2-9H,15H2,1H3,(H,16,17)

InChIKey

WDOCBIHNYYQINH-UHFFFAOYSA-N

Smiles

c1(ccc(cc1)N)S(c1ccc(NC(C)=O)cc1)(=O)=O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 10gm/kg (10000mg/kg)   Therapie. Vol. 6, Pg. 251, 1951.

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) 0.800 (none)   EST
Water Solubility 71 mg/L 37 EXP
Atmospheric OH Rate Constant 2.58E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.