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Substance Name: Viridinomycin
RN: 56509-88-7
UNII: ROF8L540EA
InChIKey: GWYPHKYSRIAIBU-KGZNJIQESA-N

Note

  • Crystalline antibiotic isolated from culture broth of Streptomyces viridochromogenes strain no. T-24146.

Molecular Weight

  • 555.6673
 

Classification Codes

  • Drug / Therapeutic Agent
  • Natural Product
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Names and Synonyms

Name of Substance

  • Viridinomycin

Synonyms

  • Antibiotic T-24146
  • UNII-ROF8L540EA
  • Viridomycin

Systematic Name

  • Viridenomycin

Registry Numbers

CAS Registry Number

  • 56509-88-7

FDA UNII

  • ROF8L540EA

System Generated Number

  • 0056509887

Structure Descriptors

InChI

1S/C34H37NO6/c1-25-19-13-8-4-5-9-16-22-27(26-20-14-12-15-21-26)35-28(36)23-17-10-6-7-11-18-24-34(2)29(33(39)41-25)30(37)31(40-3)32(34)38/h4-21,23-24,27,31-32,37-38H,22H2,1-3H3,(H,35,36)/b5-4+,10-6-,11-7+,13-8+,16-9-,23-17-,24-18+,25-19+/t27?,31-,32+,34+/m0/s1

InChIKey

GWYPHKYSRIAIBU-KGZNJIQESA-N

Smiles

CO[C@@H]1[C@@H](O)[C@]2(C)\C=C\C=C\C=C/C=C\C(=O)NC(C\C=C/C=C/C=C/C=C(\C)/OC(=O)C2=C1O)c3ccccc3

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 250mg/kg (250mg/kg)   "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 2, Pg. 1206, 1978.
mouse LD50 oral 2gm/kg (2000mg/kg)   "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 2, Pg. 1206, 1978.
mouse LD50 subcutaneous 250mg/kg (250mg/kg)   "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 2, Pg. 1206, 1978.