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Substance Name: Flurbiprofen sodium [USP]
RN: 56767-76-1
UNII: M3QE6AS001
InChIKey: AUAGTGKMTMVIKN-UHFFFAOYSA-M

Note

  • An anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.

Molecular Formulas

  • C15-H12-F-O2.Na
  • C15-H13-F-O2.Na

Molecular Weight

  • 266.2458
 

Classification Codes

  • Drug / Therapeutic Agent
  • Inhibitor (Prostaglandin Synthesis)

Names and Synonyms

Name of Substance

  • Flurbiprofen sodium [USP]

Synonyms

  • 2-Fluoro-alpha-methyl-4-diphenylacetic acid sodium salt
  • EINECS 260-373-2
  • Flurbiprofen sodium
  • Flurbiprofen sodium salt
  • Ocufen
  • Sodium 2-fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetate
  • Sodium 3-fluoro-4-phenylhydratropate
  • Sodium flurbiprofen
  • UNII-M3QE6AS001

Systematic Names

  • (1,1'-Biphenyl)-4-acetic acid, 2-fluoro-alpha-methyl-, sodium salt
  • Sodium 2-fluoro-alpha-methyl(1,1'-biphenyl)-4-acetate

Registry Numbers

CAS Registry Number

  • 56767-76-1

FDA UNII

  • M3QE6AS001

System Generated Number

  • 0056767761

Molecular Formulas

Molecular Formulas

  • C15-H12-F-O2.Na
  • C15-H13-F-O2.Na

Molecular Formula Fragments

  • C15-H12-F-O2
  • C15-H13-F-O2
  • COMPONENT
  • Na

Structure Descriptors

InChI

1S/C15H13FO2.Na/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11;/h2-10H,1H3,(H,17,18);/q;+1/p-1

InChIKey

AUAGTGKMTMVIKN-UHFFFAOYSA-M

Smiles

CC(c1ccc(c(c1)F)c2ccccc2)C(=O)[O-].[Na+]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 240mg/kg (240mg/kg)   United States Patent Document. Vol. #4613505,
mouse LD50 oral 436mg/kg (436mg/kg)   United States Patent Document. Vol. #4613505,