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Substance Name: Streptovirudin
RN: 56833-74-0
InChIKey: VFVPUOZOQGGMBI-OJYBKPOHSA-N

Note

  • New antibiotics with antiviral activity isolated from Streptomyces grisoflavus.

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • Unspecified

Molecular Weight

  • 720.7212
 
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Names and Synonyms

Name of Substance

  • Streptovirudin

Systematic Name

  • Streptovirudin

Registry Numbers

CAS Registry Number

  • 56833-74-0

System Generated Number

  • 0056833740

Structure Descriptors

InChI

1S/C30H48N4O16/c1-11(2)5-4-6-16(38)32-19-23(43)20(40)14(47-29(19)50-28-18(31-12(3)36)22(42)21(41)15(10-35)48-28)9-13(37)26-24(44)25(45)27(49-26)34-8-7-17(39)33-30(34)46/h4,6,11,13-15,18-29,35,37,40-45H,5,7-10H2,1-3H3,(H,31,36)(H,32,38)(H,33,39,46)/b6-4+/t13?,14-,15+,18+,19-,20+,21+,22+,23-,24+,25-,26-,27-,28?,29+/m1/s1

InChIKey

VFVPUOZOQGGMBI-OJYBKPOHSA-N

Smiles

CC(C)C/C=C/C(=O)N[C@@H]1[C@H]([C@H]([C@H](O[C@H]1OC2[C@H]([C@@H]([C@H]([C@@H](O2)CO)O)O)NC(=O)C)CC([C@@H]3[C@H]([C@H]([C@@H](O3)N4CCC(=O)NC4=O)O)O)O)O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 17500ug/kg (17.5mg/kg)   Journal of Antibiotics. Vol. 28, Pg. 514, 1975.
mouse LD50 oral 150mg/kg (150mg/kg)   Journal of Antibiotics. Vol. 28, Pg. 514, 1975.
mouse LD50 subcutaneous 15mg/kg (15mg/kg)   Journal of Antibiotics. Vol. 28, Pg. 514, 1975.