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Substance Name: 1,1-Dimethylhydrazine
RN: 57-14-7
UNII: 4WPQ90N53J
InChIKey: RHUYHJGZWVXEHW-UHFFFAOYSA-N

Molecular Formula

  • C2-H8-N2

Molecular Weight

  • 60.0992
 

Classification Codes

Classification Codes

  • Mutation Data
  • Reproductive Effect
  • Tumor Data

Superlist Classification Codes

  • Overall Carcinogenic Evaluation: Group 2B
  • Reasonably Anticipated to be a Carcinogen
  • Reportable Quantity (RQ) = 10 lb
  • Threshold Planning Quantity (TPQ) = 1000 lb
  • TWA (0.01 ppm); skin; Confirmed animal carcinogen with unknown relevance to humans
  • TWA 0.5 ppm (1 mg/m3); skin

Names and Synonyms

Name of Substance

  • 1,1-Dimethylhydrazine
  • Dimazine

Synonyms

  • 1,1-Dimethylhydrazin
  • 1,1-Dimethylhydrazin [German]
  • 1,1-Dimethylhydrazine
  • 4-04-00-03322 (Beilstein Handbook Reference)
  • as-Dimethyl hydrazine
  • asymmetric Dimethylhydrazine
  • asymmetric-Dimethylhydrazine
  • BRN 0605261
  • CCRIS 258
  • Dimazine
  • Dimethylhydrazine unsymmetrical
  • Dimethylhydrazine, unsym.
  • EC 200-316-0
  • EINECS 200-316-0
  • gem-Dimethylhydrazine
  • HSDB 528
  • Hydrazine, 1,1-dimethyl-
  • Hydrazine, N,N-dimethyl-
  • N,N-Dimethylhydrazine
  • N,N-Dimetilidrazina
  • N,N-Dimetilidrazina [Italian]
  • Niesymetryczna dwu metylohydrazyna
  • Niesymetryczna dwu metylohydrazyna [Polish]
  • NSC 60517
  • RCRA waste number U098
  • u-Dimethylhydrazine
  • UDMH
  • UNII-4WPQ90N53J
  • uns-Dimethylhydrazine
  • Unsymmetrical dimethylhydrazine
  • unsymmetrical-Dimethylhydrazine

Systematic Names

  • 1,1-Dimethylhydrazine
  • Hydrazine, 1,1-dimethyl-
  • N,N-Dimethylhydrazine

Superlist Names

  • 1,1-Dimethyl hydrazine
  • 1,1-Dimethylhydrazine
  • Dimethylhydrazine, unsymmetrical
  • Dimethylhydrazine, unsymmetrical [UN1163] [Poison]
  • Hydrazine, 1,1-dimethyl-
  • RCRA waste no. U098
  • UDMH
  • UN1163

Registry Numbers

CAS Registry Number

  • 57-14-7

FDA UNII

  • 4WPQ90N53J

Other Registry Number

  • 88733-28-2

Related Registry Numbers

  • 55484-54-3 (di-hydrochloride)
  • 593-82-8 (hydrochloride)

System Generated Number

  • 0000057147

Structure Descriptors

InChI

1S/C2H8N2/c1-4(2)3/h3H2,1-2H3

InChIKey

RHUYHJGZWVXEHW-UHFFFAOYSA-N

Smiles

N(C)(C)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intraperitoneal 30mg/kg (30mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS

VASCULAR: REGIONAL OR GENERAL ARTERIOLAR OR VENOUS DILATION

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)		 European Journal of Toxicology and Environmental Hygiene. Vol. 7, Pg. 238, 1974.
dog LC50 inhalation 3580ppm/15M (3580ppm) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BEHAVIORAL: TREMOR		 American Industrial Hygiene Association Journal. Vol. 24, Pg. 137, 1963.
dog LD50 intraperitoneal 60mg/kg (60mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: NAUSEA OR VOMITING		 National Technical Information Service. Vol. AD292-689,
dog LD50 intravenous 60mg/kg (60mg/kg)   Medycyna Pracy. Industrial Medicine. Vol. 24, Pg. 71, 1973.
dog LDLo skin 301mg/kg (301mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Toxicology and Applied Pharmacology. Vol. 18, Pg. 649, 1971.
guinea pig LC50 inhalation 100mg/m3/4H (100mg/m3)   Toksikologicheskii Vestnik. Vol. (6), Pg. 39, 1999.
guinea pig LD50 skin 1329mg/kg (1329mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD U.S. Army Chemical Warfare Laboratories. Vol. CWL,
hamster LC50 inhalation 392ppm/4H (392ppm) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD AMA Archives of Industrial Health. Vol. 12, Pg. 609, 1955.
hamster LD50 subcutaneous 325mg/kg (325mg/kg)   Cancer Letters Vol. 35, Pg. 303, 1987.
human TDLo unreported 10mg/kg (10mg/kg) LIVER: LIVER FUNCTION TESTS IMPAIRED

BEHAVIORAL: HEADACHE

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 "Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 71, 1999.
monkey LD50 intraperitoneal 60mg/kg (60mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD		 National Technical Information Service. Vol. AD292-689,
mouse LC50 inhalation 172ppm/4H (172ppm) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 AMA Archives of Industrial Health. Vol. 12, Pg. 609, 1955.
mouse LD50 intraperitoneal 113mg/kg (113mg/kg) SKIN AND APPENDAGES (SKIN): HAIR: OTHER

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE		 Proceedings of the Society for Experimental Biology and Medicine. Vol. 124, Pg. 172, 1967.
mouse LD50 intravenous 250mg/kg (250mg/kg)   Medycyna Pracy. Industrial Medicine. Vol. 24, Pg. 71, 1973.
mouse LD50 oral 155mg/kg (155mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD		 "Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 71, 1999.
rabbit LD50 skin 1060mg/kg (1060mg/kg)   "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986Vol. 5, Pg. 210.1(89), 1986.
rat LC50 inhalation 252ppm/4H (252ppm) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 AMA Archives of Industrial Health. Vol. 12, Pg. 609, 1955.
rat LD50 intraperitoneal 102mg/kg (102mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Toxicology and Applied Pharmacology. Vol. 6, Pg. 371, 1964.
rat LD50 intravenous 119mg/kg (119mg/kg)   Medycyna Pracy. Industrial Medicine. Vol. 24, Pg. 71, 1973.
rat LD50 oral 122mg/kg (122mg/kg)   Medycyna Pracy. Industrial Medicine. Vol. 24, Pg. 71, 1973.
rat LD50 skin 770mg/kg (770mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BLOOD: CHANGES IN BONE MARROW NOT INCLUDED ABOVE

BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS		 "Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 71, 1999.
rat LDLo intracrebral 27mg/kg (27mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Biochemical Pharmacology. Vol. 14, Pg. 1901, 1965.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -5.80E+01 deg C   EXP
Boiling Point 63.9 deg C   EXP
pKa Dissociation Constant 7.21 (none) 25 EXP
log P (octanol-water) -1.190 (none)   EST
Water Solubility 1.00E+06 mg/L   EXP
Vapor Pressure 157 mm Hg 25 EXP
Henry's Law Constant 1.24E-05 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 2.53E-12 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.