Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Amiloride hydrochloride mixture with Hydrochlorothiazide
RN: 57017-78-4
InChIKey: QRDAGKVHMGNVHB-UHFFFAOYSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Human Data

Molecular Formula

  • C7-H8-Cl-N3-O4-S2.C6-H8-Cl-N7-O.Cl-H

Molecular Weight

  • 563.8333
 
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Amiloride hydrochloride mixture with Hydrochlorothiazide

Synonyms

  • Ameride
  • Amilco
  • Amiloride and hydrochlorothiazide
  • Amiloride hydrochloride and hydrochlorothiazide
  • Amiloride hydrochloride-hydrochlorothiazide
  • Amitrid
  • Hydro-Ride
  • Hypertane
  • Kaluril
  • Moduret 25
  • Moduretic
  • Moduretic 5-50

Systematic Name

  • Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, monohydrochloride, mixt. with 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazene-7-sulfonamide 1,1-dioxide

Registry Numbers

CAS Registry Number

  • 57017-78-4

Other Registry Number

  • 156014-85-6

Related Registry Number

  • 68529-45-3 (Parent)

System Generated Number

  • 0057017784

Molecular Formulas

Molecular Formula

  • C7-H8-Cl-N3-O4-S2.C6-H8-Cl-N7-O.Cl-H

Molecular Formula Fragments

  • C6-H8-Cl-N7-O
  • C7-H8-Cl-N3-O4-S2
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C7H8ClN3O4S2.C6H8ClN7O.ClH/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5;7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11;/h1-2,10-11H,3H2,(H2,9,12,13);(H4,8,9,13)(H4,10,11,14,15);1H

InChIKey

QRDAGKVHMGNVHB-UHFFFAOYSA-N

Smiles

c1c2c(cc(c1Cl)S(=O)(=O)N)S(=O)(=O)NCN2.c1(c(nc(c(n1)Cl)N)N)C(=O)NC(=N)N.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo oral 71mg/kg/90D-I (71mg/kg)   Postgraduate Medical Journal. Vol. 56, Pg. 348, 1980.
man TDLo oral 71mg/kg/90D-I (71mg/kg) KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" Postgraduate Medical Journal. Vol. 56, Pg. 348, 1980.
women TDLo oral 5500ug/kg/5D- (5.5mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

BEHAVIORAL: HEADACHE
Lancet. Vol. 2, Pg. 634, 1986.